Cardiovascular Flashcards
Cardiac action potential
-rapid change in membrane potential, or voltage, across the cardiac cell membrane
-triggers cardiac muscle contraction
Resting membrane potential
-when cardiac call of the ventricle is not electrically excited
-phase 4 (-90mV)
Main ion found outside the cell at rest
Sodium and Chloride
Main ion found inside the cell at rest
Potassium
Threshold potential
The critical level a membrane potential must reach to initiate an action potential
Depolarization
-phase 0
-voltage becomes more positive
-sodium influx
-potassium eflux
-rapid inactivation of sodium channels cause membrane potential to return to a negative state
Repolarization
-phase 1
Define preload
Volume present in the ventricle prior to systole (volume filling the heart)
Define afterload
Load (pressure) that the heart must pump against in order to eject blood
Define contractility
Intrinsic force of the heart - degree of which the sarcomeres can shorten
What are sympathetic nervous system effects on the heart
Increased contractility, increased HR
What are parasympathetic nervous system effects on the heart
Decreased chronotropy (HR) and contractility
Draw a ventricular action potential
Describe the flow of blood through the heart
cranial/caudal vena cava > right atrium > tricuspid valve > right ventricle > pulmonic valve > pulmonary artery > pulmonary vein > left atrium > mitral valve > left ventricle > aortic valve > aorta
Where can arterial catheters be placed
Dorsal pedal
Femoral
Auricular
Coccygeal
Lingual
What are the components of an arterial wave form
What are possible pulse abnormalities
Hypodynamic (decreased pulse pressure)
Hyperdynamic (increased pulse pressure due to decreased diastolic pressure)
Bounding (increased pulse pressure due to increased systolic pressure)
Pulses paradoxus - decrease in BP > 10 mmHg during inspiration
What are the types of cardiac hypertrophy?
Concentric - increased pressure overload (HCM)
Eccentric - increased volume overload (DCM)