Coagulation QUIZ/Lab Flashcards

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1
Q

A coagulation test that used a tube containing diatomaceous earth and a heat block (or armpit) is the:
1. Partial Thromboplastin (PTT)
2. Buccal Mucosal Bleeding Time (BMBT)
3. Prothrombin Time (PT)
4. Activated Clotting Time (ACT)

A

Activated Clotting Time (ACT)

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2
Q

A coagulation test that evaluates the extrinsic pathway is:
1. Activated Clotting Time (ACT)
2. Partial Thromboplastin (PTT)
3. Prothrombin time (PT)
4. Buccal Mucosal Bleeding Time (BMBT)

A

Prothrombin time (PT)

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3
Q

The d-Dimer and fibrin degradation product (FDP) tests can be used to evaluate:
1. Macrophage Dysfunction
2. regenerative anemia
3. platelet function
4. fibrinolysis

A
  1. fibrinolysis
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4
Q

PIVKA is an acronym for:
1. proteins induced by kalikrin activity
2. proteins induced by vitamin K activation
3. proteins induced by variable kinetic aggregates
4. proteins induced by vitamin K absence

A
  1. proteins induced by vitamin K absence
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5
Q

List three possible causes of coagulopathies

A

Your answer:
rat poison, tick-borne, birth defect (hemophilia)

Instructor:
a. Platelet disorder (low count (ITP); or ineffective (VonWillebrands)

b. Clotting factor disorder (Hemophilia, Liver Failure, Rodenticide toxicity)

c. Abnormal Fibrinolysis (DIC, Snake Venom)

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6
Q

The body needs a minimum number of platelets to protect against inappropriate bleeding.
1. >350,000
2. >250,000
3. >50,000
4. >150,000

A

> 50,000

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7
Q

Agents in blood collection tubes, such as EDTA or Citrate, prevent clotting by binding:
1. iron
2. tissue factor
3. calcium
4. platelets

A
  1. calcium
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8
Q

What are the three necessary properties for coagulation to be appropriate for effective and safe homeostasis?

A

a. rapid response

b. localized

c. reversible

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9
Q

There are 3 major body systems involved in coagulation.
a.

b. platelets

c. coagulation factors

A

Vessel walls

AKA: blood vessel endothelium (much chemical signaling in addition to vasoconstriction)

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10
Q

What are the 3 pathways in the Coagulation Cascade?
a. Extrinsic Pathway
b.
c.

A

b. Intrinsic Pathway
c. Common Pathway

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11
Q

What is ACT specifically evaluating in the Px?

A

Every clinical significant clotting factor except #7

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12
Q

Normal range for dogs in the ACT test? In seconds

A

60 to 120 seconds

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13
Q

During a sline test, how does a vet tech determine the difference between rouleaux (stacking RBC) and agglutination of RBCs?

A
  • Agg: Saline won’t break it apart. Will remain in it’s “grape” like clumps.
  • Rouleaux: Saline will disperse the formations
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14
Q

What is the clinical importance of agglutination?

A
  • It is life threatening in most species! Exception being cats and horses.
  • It lets us know if there are anitB against the RBCs
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15
Q

Name three sites to place pluse ox readers

A

tongue, ear, paw pads

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16
Q

What does the pulse ox eval? How does it work?

A
  • Eval saturation of hemoglobin
  • Relying on light absorption passing thru the Px/reflected by tissues
17
Q

If the SPO2 is 94%, what does this mean?

A

Mild hypoxemia, low oxygen