Coagulation QUIZ/Lab Flashcards
A coagulation test that used a tube containing diatomaceous earth and a heat block (or armpit) is the:
1. Partial Thromboplastin (PTT)
2. Buccal Mucosal Bleeding Time (BMBT)
3. Prothrombin Time (PT)
4. Activated Clotting Time (ACT)
Activated Clotting Time (ACT)
A coagulation test that evaluates the extrinsic pathway is:
1. Activated Clotting Time (ACT)
2. Partial Thromboplastin (PTT)
3. Prothrombin time (PT)
4. Buccal Mucosal Bleeding Time (BMBT)
Prothrombin time (PT)
The d-Dimer and fibrin degradation product (FDP) tests can be used to evaluate:
1. Macrophage Dysfunction
2. regenerative anemia
3. platelet function
4. fibrinolysis
- fibrinolysis
PIVKA is an acronym for:
1. proteins induced by kalikrin activity
2. proteins induced by vitamin K activation
3. proteins induced by variable kinetic aggregates
4. proteins induced by vitamin K absence
- proteins induced by vitamin K absence
List three possible causes of coagulopathies
Your answer:
rat poison, tick-borne, birth defect (hemophilia)
Instructor:
a. Platelet disorder (low count (ITP); or ineffective (VonWillebrands)
b. Clotting factor disorder (Hemophilia, Liver Failure, Rodenticide toxicity)
c. Abnormal Fibrinolysis (DIC, Snake Venom)
The body needs a minimum number of platelets to protect against inappropriate bleeding.
1. >350,000
2. >250,000
3. >50,000
4. >150,000
> 50,000
Agents in blood collection tubes, such as EDTA or Citrate, prevent clotting by binding:
1. iron
2. tissue factor
3. calcium
4. platelets
- calcium
What are the three necessary properties for coagulation to be appropriate for effective and safe homeostasis?
a. rapid response
b. localized
c. reversible
There are 3 major body systems involved in coagulation.
a.
b. platelets
c. coagulation factors
Vessel walls
AKA: blood vessel endothelium (much chemical signaling in addition to vasoconstriction)
What are the 3 pathways in the Coagulation Cascade?
a. Extrinsic Pathway
b.
c.
b. Intrinsic Pathway
c. Common Pathway
What is ACT specifically evaluating in the Px?
Every clinical significant clotting factor except #7
Normal range for dogs in the ACT test? In seconds
60 to 120 seconds
During a sline test, how does a vet tech determine the difference between rouleaux (stacking RBC) and agglutination of RBCs?
- Agg: Saline won’t break it apart. Will remain in it’s “grape” like clumps.
- Rouleaux: Saline will disperse the formations
What is the clinical importance of agglutination?
- It is life threatening in most species! Exception being cats and horses.
- It lets us know if there are anitB against the RBCs
Name three sites to place pluse ox readers
tongue, ear, paw pads