Coagulation QUIZ/Lab

Question 1

A coagulation test that used a tube containing diatomaceous earth and a heat block (or armpit) is the:
1. Partial Thromboplastin (PTT)
2. Buccal Mucosal Bleeding Time (BMBT)
3. Prothrombin Time (PT)
4. Activated Clotting Time (ACT)

Answer 1

Activated Clotting Time (ACT)

Question 2

A coagulation test that evaluates the extrinsic pathway is:
1. Activated Clotting Time (ACT)
2. Partial Thromboplastin (PTT)
3. Prothrombin time (PT)
4. Buccal Mucosal Bleeding Time (BMBT)

Answer 2

Prothrombin time (PT)

Question 3

The d-Dimer and fibrin degradation product (FDP) tests can be used to evaluate:
1. Macrophage Dysfunction
2. regenerative anemia
3. platelet function
4. fibrinolysis

Answer 3

4. fibrinolysis

Question 4

PIVKA is an acronym for:
1. proteins induced by kalikrin activity
2. proteins induced by vitamin K activation
3. proteins induced by variable kinetic aggregates
4. proteins induced by vitamin K absence

Answer 4

4. proteins induced by vitamin K absence

Question 5

List three possible causes of coagulopathies

Answer 5

Your answer:
rat poison, tick-borne, birth defect (hemophilia)

Instructor:
a. Platelet disorder (low count (ITP); or ineffective (VonWillebrands)

b. Clotting factor disorder (Hemophilia, Liver Failure, Rodenticide toxicity)

c. Abnormal Fibrinolysis (DIC, Snake Venom)

Question 6

The body needs a minimum number of platelets to protect against inappropriate bleeding.
1. >350,000
2. >250,000
3. >50,000
4. >150,000

Answer 6

> 50,000

Question 7

Agents in blood collection tubes, such as EDTA or Citrate, prevent clotting by binding:
1. iron
2. tissue factor
3. calcium
4. platelets

Answer 7

3. calcium

Question 8

What are the three necessary properties for coagulation to be appropriate for effective and safe homeostasis?

Answer 8

a. rapid response

b. localized

c. reversible

Question 9

There are 3 major body systems involved in coagulation.
a.

b. platelets

c. coagulation factors

Answer 9

Vessel walls

AKA: blood vessel endothelium (much chemical signaling in addition to vasoconstriction)

Question 10

What are the 3 pathways in the Coagulation Cascade?
a. Extrinsic Pathway
b.
c.

Answer 10

b. Intrinsic Pathway
c. Common Pathway

Question 11

What is ACT specifically evaluating in the Px?

Answer 11

Every clinical significant clotting factor except #7

Question 12

Normal range for dogs in the ACT test? In seconds

Answer 12

60 to 120 seconds

Question 13

During a sline test, how does a vet tech determine the difference between rouleaux (stacking RBC) and agglutination of RBCs?

Answer 13

• Agg: Saline won’t break it apart. Will remain in it’s “grape” like clumps.
• Rouleaux: Saline will disperse the formations

Question 14

What is the clinical importance of agglutination?

Answer 14

• It is life threatening in most species! Exception being cats and horses.
• It lets us know if there are anitB against the RBCs

Question 15

Name three sites to place pluse ox readers

Answer 15

tongue, ear, paw pads

Question 16

What does the pulse ox eval? How does it work?

Answer 16

• Eval saturation of hemoglobin
• Relying on light absorption passing thru the Px/reflected by tissues

Question 17

If the SPO2 is 94%, what does this mean?

Answer 17

Mild hypoxemia, low oxygen