CO2 + O2 (Colombo) Week 3 Flashcards

1
Q

Give the defintion of Partial Pressure

A

The pressure of an INDIVIDUAL gas in a fiven volume at a constant pressure

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2
Q

What is the difference between alveolar air and atmospheric air?

A

Alveolar air contains CO2 and H20, they make up a small portion but they end up diluting the O2 and N2 from the atmospheric air

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3
Q

How can the distance of diffusion pathologically increased?

A

By damage to the alveoli, pulmonary diseases will cause this. Making it harder for O2 to diffuse into the blood.

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4
Q

Define Tidal Volume

A

Normal volume of air dispalced between inhalation and exhalation.

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5
Q

What is Functional residual capacity

A

part of tidal volume, allows for there to not be any sudden changes or irregularites keeping the blood gas levels constant.

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6
Q

What are the 2 factors that control the amount of o2 in the alveoli

A
  1. Ventilartion

2. Rate of absorption from blood.

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7
Q

What happens when there is a high metabolic demand to o2 and co2

A

o2 - decreases amount in blood

co2 - increases amount in blood.

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8
Q

What is the Ventilation/Perfusion Ratio?

A

The relationship between alveolar ventilation &a alveolar perfusion.

(doesnt matter how much air you can get into your lungs if the o2 cant perfuse into bloodstream)

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9
Q

VA/Q

A
VA = Ventilation
Q = Blood flow
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10
Q

What is Shunted blood and what is the Physiologic Shunt

A

Shunted Blood is the non-perfused blood

Physiologic shunt is the amount of shunted blood that passes throught the circulatorysystem/minute

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11
Q

What 2 factors effect the transport of blood gases?

A
  1. Rate of diffusion

2. movement of blood

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12
Q

What is the partial pressure of O2 when leaving alveoli?/Returning?

A

104mm Hg

40 mm Hg

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13
Q

What makes it so O2 can be soluble in blood

A

RBC’s have Hemaglobin hich have an affinity for O2.

However the affinity varies depending on concenctration of O2 in blood

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14
Q

Describe the Hemoglobin O2 affinity

A

High PP O2 favor Hb binding

Low = favor O2 disassociation

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15
Q

Define Cooperative Binding

A

The more O2 HB has the easier it is for another O2 molecule to bind.

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16
Q

How many binding sites does Hb have?

A

4 - each site has 2 O2 molecules resulting in a total of 8 O2 molecules if full.

17
Q

How much more soluble is Co2 than O2

A

20x more than O2

18
Q

Haldane effect vs Bohr effect

A

Haldane = states deoxygenated blood has an increased ability to carry carbon dioxide

Bohr = relates to how pH and CO2 affect the capacity to carry O2
(low pH = less O2 affinity)