CNS Stimulants (Iszard) Flashcards
Basic action of stimulants
enhance neurotransmitter transmission by serving as direct and indirect non-catecholamine sympathomimetics
normal side effects of stimulants (6)
- dyspepsia/GI distress
- headache
- decreased appetite
- insomnia
- anxiety
- elevated BP/HR
rare side effects of stimulants (5)
- priapism
- seizures
- sudden cardiac death
- stroke/MI
- chemical leukoderma (with patch use)
onset of activity of stimulants
24 hours in most patients
Prescribing stimulants
stimulants are CONTROLLED SUBSTANCES (1 month supply only, no refills, no samples)
Immediate release amphetamine-based stimulant that comes in LIQ form
Dextroamphetamine sulfate/Procentra
Extended release amphetamine-based stimulant that comes in LIQ form
Amphetamine/Dyanavel XR
Oral disintegrating tab form of amphetamine
Adzenyz XR-ODT
immediate release, methylphenidate-based stimulant in LIQ form
Methylphenidate/Methylin Oral Solution
extended release, methylphenidate-based stimulant in transdermal patch form
methylphenidate transdermal/daytrana
extended release, methylphenidate-based stimulant in chewable tablet form
methylphenidate HCL/QuilliChew
extended release, methylphenidate-based stimulant in liquid form
methylphenidate/Quillivant XR
MOA non-stimulants (for ADHD)
enhance neurotransmitter transmission via:
1) inhibition of NE pre-synaptic reuptake
2) agonists of CNS alpha-2 adrenergic receptors
onset of activity for non-stimulants
1-4+ weeks
When to use non-stimulants
useful for patients intolerant of stimulant effects or parents/patients resistant to using stimulant-class