CNS Infections Flashcards

1
Q

What are the Meningeal signs?

A
  • Nuchal rigidity
  • Kernig sign
  • Brudzky’s sign
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2
Q

What is nuchal rigidity?

A

Pt supine, try to flex neck & meet resistance

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3
Q

What is Kernig sign?

A

Flex hip to 90° & extend the knee→ causes pain

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4
Q

What is Brudzky’s sign?

A

Pt supine, flex neck & pt pulls legs up (bend @ hips & knees)

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5
Q

What is a fever?

A

T >99.2° in AM or T>99.9° in PM

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6
Q

What are the Inc ICP signs?

A
  • HA worse supine & in PM
  • N/V
  • Lethargic to coma
  • Pailledema
  • Lateral rectus pasly: estropia
  • Blurred vision
  • Cushings triad
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7
Q

What is Cushing’s Triad?

A

HTN, bradycardia & Resp irreg

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8
Q

What is the hx of Aseptic meningits (viral)?

A
  • HA
  • Neck pain & stiffness
  • Acute or subacute onset
  • Malaise
  • N/V/D
  • Hx of preceding URI
  • Check hx of NSAID use
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9
Q

What are the PE findings of Aseptic meningitis (viral)?

A
  • Fairly normal mental status or mildy lethargic or irritable
  • Normal neuro exam
    • nuchal rigidity
    • photphobia
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10
Q

What are the CSF findings in Aseptic meningitis?

A
  • Opening pressure mildly-mod inc
  • Clear, colorless
  • WBC count normal or inc
  • Protein inc
  • Glucose normal
  • Culture neg
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11
Q

What are the PE findings of Bacterial meningitis?

A
  • Acute or subacute
  • Fever & HA
  • Neck pain
  • N/V
  • Photophobia
  • Altered mental status
  • Seizures
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12
Q

When should a CT scan be performed prior to an LP in bacterial meningitis?

A
  • Immunocompromised pt
  • Focal neuro signs
  • Altered mental status
  • Papilledema
  • Hx of recent head trauma
  • Seizures
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13
Q

What are the CSF findings of bacterial meningitis?

A
  • Elevated opening pressure
  • Elevated WBC count w/ neutrophils
  • Low glucose
    • gram stain
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14
Q

When should empirical antimicrobial therapy be started in bacterial meningitis?

A

As soon as the dx is suspected

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15
Q

What are the PE findings of Viral encephalitis or meningoencephaltis?

A
  • More profound mental status changes
  • More freq seizures, CN ABN & focal neuro deficits
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16
Q

What are the Tech features of viral encephalitis or meningoencephalitis?

A
  • Brain imaging before LP
  • MRI + in HSV encephalitis
17
Q

What are the PE findings of Subacute Meningitis?

A
  • Subacute or chronic
  • Stiff neck
  • Low grade fever
  • Lethargy & mental status changes
  • Freq hx of IC status
  • Night sweats
  • Pulmonary sx
  • CN ABN
18
Q

What are the CSF findings of subacute meningitis (fungal or TB)?

A
  • Elevated opening pressure
  • Lymphocytic pleocytosis
  • Inc protein
  • Low glucose
    • Acid fast or TB culture
    • India ink & + cryptococcus capusular Ag in neofroman meningitis
19
Q

What are the sx of Brain abscess?

A
  • Subacute or gradual
  • HA MC presenting sx
  • Focal neuro sx & seizures common
  • Sx get progressively worse
20
Q

What is the hx of Brain abscess?

A

Preceding sinus, dental or ear infections, mastoidits, pulmonary infections or recent dental or neurosurgical procedures

21
Q

What are the PE findings of brain abscess?

A
  • Fever in <50% of time
  • Focal neuro deficits are common & depend on abscess location
22
Q

What is the most sensitive imaging for Brain abscess?

A

MRI w/ & w/o contrast

23
Q

What is the duration of SC abscess?

A

Subacute or gradual

24
Q

What do SC abscess follow?

A

Brain abscess w/ hematogenous spread to SC in epidural area or spinal surgery or trauma

25
Q

What are the PE findings of SC abscess?

A
  • Poly-radicular findings
  • Myelopathic findings if lesion enroaches on SC
  • Fever absent
26
Q

What are the Tech features of SC abscess?

A
  • MRI is best–epidural mass found
  • Needle aspiration reveals suppurative process
  • Organism ID on bx
27
Q

What is the tx of SC abscess?

A

ABX base on organism or surgical decompression