CNS - Drugs for antidepressants Flashcards

1
Q

what do SSRIs stand for?

A

Selective Seretonin Reuptake Inhibitors

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2
Q

What are the SSRIs?

A

Fluo|xetine
Paro|xetine

Ser|tara|line

Cita|lopram
ES|citalopram

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3
Q

what is the MoA of SSRIs?

A

block serotonin reabsorption into presynaptic nerve ending
= increase [serotonin] in synaptic cleft
= increase serotonin activity at the post synaptic receptor sites

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4
Q

what are the adverse effects of SSRIs

A

nausea
headache
weight loss & gain
anxiety
sexual dysfunction

**no fatility in OD

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5
Q

what does SNRIs stand for

A

serotonin norepinephrine reuptake inhibitors

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6
Q

what are the SNRI drugs?

A

vena|flaxine
tra|zodone
nefa|zodone

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7
Q

what are the TCA drugs?

A

amitriptyline
imi|pramine

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8
Q

what are the side effects of the TCAs and SNRIs?

A

CNS - sedation, fatigue
CVS - tachycardia, arrhythmia, postural hypotension
anticholinergic effects -

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9
Q

definition of anticholinergic

A

block acetylcholine
= cannot have parasympathetic NS

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10
Q
A
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