CNS Classes 4-6 Flashcards
________ modulation; modifiers of afferent transmission as it travels from the tissues to the brain eg: local inhibition in the dorsal horn and
ascending
______ modulation takes place in the CNS
descending
endogenous opioids released by the brain are called ______ & ______ these are the bodies version of morphine or heroin
endorphins & enkephalins
the ______ initiates a complex intercommunication process that results in the release of modulators from brainstem zones like the raphe nuclei
PAG (periaqueductal grey area)
T/F the PAG “closes the gate” and inhibits the firing of second-order neurons themselves
true
_______ & ________ can also produce effects in the spinal cord
endorphins and enkephalins
T/F endorphins and enkephalins can be impaired by different traumas and pathologies
true
which of the following can alter central modulation in ways that affect the sensory experience?
a) mood
b) mental health
c) traumatic history
d) all of the above
d) all of the above
T/F anxiety does not increase one’s experience of pain
false
T/F the predominance in the sympathetic nervous system activation enhances pain perception
true
_____ ______ is rendered less effective especially if dysfunctional stress becomes entrenches and when anxiety is present
central modulation
_______ _________; signals coming from sensory receptors along first-order neurons, these are normal and should not cause pain
Central sensitization
in the ______ horn of the spinal cord signals of central sensitization are amplified and by the time they reach the brain what should have been a normal message is transformed into a message of pain
dorsal
T/F central sensitization is often used to describe situations where a persons history of physical or emotional trauma creates hyper facilitation of pain along with reduced descending modulation
true
central sensitization mechanisms can be completed by _____ _____ and ______
speed sequencing and synchronicity
speed sequencing and synchronicity means the person is expressing mental or emotional distress as ______ symptoms
physical
T/F central sensitization is linked to anxiety and depression
true
anxiety, pain and distress cause depression by depleting ______, ______, endogenous opioids and norepinephrine volumes in the CNS
serotonin, dopamine
T/F there are many ways that damage and disease can add to the brains interpretation difficulties
true
some things that may cause brain interpretation difficulties include ______ loss, inflammation & _______
neuron loss, inflammation and edema
ischemia, compression, and demyelination are additional factors causing _____ challenges
interpretation
T/F a cluster of demyelinated axons will transmit slower than same function neurons that are intact
true
when a cluster of demyelinated axons are transmitting, rather than receiving information smoothly, the ______ receives info in disordered batches producing a more confusing interpretation
thalamus
______ pain, a common phenomenon where there is irritation/ damage in the sensory nervous system
neuropathic
_______ is the absence of any sensation; stimulus does not produce any of the expected sensation
anaesthesia
________ is diminished sensation; the experience matches the nature of the stimulus but less strong than expected
hypaesthesia
________; heightened or exaggerated sensation
hyperaesthesia
_______; abnormal sensation e.g pins and needles, ants crawling on skin
paraesthesia
________; when a paresthetic sensation is painful, can be described as hot pokers, electric burning etc.
dysaesthesia
___________; instead of the expected sensation, an innocuous stimulus results in pain
dysdiadochokinesia
________; this can be caused by local nerve damage or irritation, problems in the CNS or central modulation
Allodynia
________; when the response to a stimulus is weak, and the sensation experienced is not as strong as predicted
hypalgesia
_________, heightened sensitivity to painful stimuli, unexpectedly strong pain intensity
hyperalgesia/hyperalgia
the ______ ______ is the “ceo” of the brain
motor cortex
T/F the motor cortex is involved in controlling voluntary movements
true
the motor cortex is in charge of carrying out _____ directed movements
goal
the primary higher motor centre for dexterity and fine motor control is the ____ ____
motor cortex
________ _______; some degree of reduced tone in the motor system, creating a lower resting tone and weaker/ slower recruitment of power
generalized hypotonia
this makes up 10% of the brain’s total volume but accounts for over 50% of its neurons
the cerebellum
responsibilities of the cerebellum include…
monitoring incoming sensory info, overall coordination
T/F the cerebellum is in charge of the body’s motor adjustment to the horizon and gravity
true
_________/________; generalized discoordination
dyssynergia/asynergia
______ ______; tremors during purposeful activity, initiating and intensifying as the activity progresses
intention tremor
________; failure to pinpoint, inability to bring a body part back to accurate efficient path to a target
dysmetria