CNS 1 - Meninges, blood supply, CSF Flashcards
The CNS is contained with which cavity?
Dorsal body cavity
Which two cavities make up the dorsal body cavity?
cranial and spinal cavity
Nerves outside _____ + ____ = PNS
Skull + vertebral column
Afferents are: ____ info from __ -> ____
Sensory, body, CNS
Efferents are: _____ info from ____ -> ___
Motor, CNS, body
Hole at bottom of skull is called?
foramen magnum
Holes between vertebrae are called?
intervertebral foramina
Nerves that exist through the bottom of the skull are called?
Cranial nerves
Nerves that exist through the holes between the vertebrae are called?
spinal nerves
CNS+PNS are made of which 2 major cell types?
Neurons and glial cells
Neuronal cells are ____ cells
signalling cells
Glial cells are ____ cells
supporting cells
Are there more glial cells or neuronal cells? By how much?
There are 4x more glial cells than neuronal cells
Grey matter is where ___ __ ___ are located
Neuronal cell bodies
White matter is where ____ ____ are located
Neuronal axons
Which cells produce CSF?
Ependymal cells
Are ependymal cells glial cells or neuronal cells?
Glial cells
Classify ependymal cells
Ciliated simple cuboidal cells
Where can ependymal cells be found?
Ependymal cells can be found in ventricles
Ventricles contain what?
Ventricles contain CSF, which is why ependymal cells are located here - they produce the csf
What is CSF?
Plasma of blood, but with few cells
How many cells does the CSF contain?
CSF contains v few cells
Ependyma cells form a barrier between what?
Ependymal cells form a barrier between the CSF and the brain
What cells form the blood brain barrier?
astrocytes
Astrocytes make contact with what?
Astrocytes make contact with blood vessels
What are astrocytes main function?
Astrocytes main function is to prevent things from poisoning neurons
How do you trick astrocytes?
You dissolve things in the membrane, which easily gets across the BBB and therefore affects neurons
Which two cells form a barrier?
Ependymal cells and astrocytes
What is the purpose of the barrier?
keeps out ions and protect neurons
What are the five CNS cell types?
Ependymal cells, astrocytes, neurons, microglial cells, oliogodendrocytes
What is the purpose of microglial cells?
Provide immune system for the brain bc immune cells cant enter the brain bc of BBB
Can immune cells enter the brain?
no
Oligodendrocytes produce what?
myelin
What is the ratio between oligodendrocytes and axons?
One oligodendrocytes for multiple axons
What are the three types of PNS cells
Myelinated neurons, schwann cells, T-cells/macrophage
skin -> _____ ____ -> integrated into _____ matter of spinal cord -> ___ send signals to _____ or ____ muscle
sensory afferents, grey, efferent, skeletal or smooth
Schwann cells are what type of cell
glial cells
Where are schwann cells located?
Schwann cells sit on internodes
What is the ratio between schwann cells and axons?
one schwann cell for one axon
Which cells fight infections in the PNS?
t-cells and macrophages
Which cells fight infections in the CNS?
microglial cells
Is regeneration faster in CNS or PNS?
PNS
What do CNS glial cells do in terms of axon growth?
CNS Glial cells inhibit axon growth
Define postmitotic
Inability to go through mitosis after maturation
Which cells are postmitotic?
CNS neurons are postmitotic
PNS neurons regrow at a speed of ___?
1mm/day
PNS glial cells produce _______ that ______-
growth factors that promote regeneration
What do macrophages do in terms of PNS regeneration?
Macrophages remove debris (i.e. dead and dying cells are removed
What is a collateral axon?
an axon branch off the main axon
PNS neurons can either ______ or sprout ______ from adjacent axons
regrow or sprout collaterals from adjacent axons
Bony protection of CNS consists of? This bony protection is contained within which cavity?
skull + vertebral column; dorsal body cavity
Cerebral cortex is the ____ _____ layer of ___ matter
superficial outer layer of grey matter
Cerebral cortex lies on top of _____ _____
Cerebral hemispheres
Cerebral cortex is responsible for what?
Thinking, voluntary movements, memory, storage, & sensory perception (TV makes me smart & stuPid)
Diencephalon is located where?
Deep within grey matter of brain, and on top of brainstem
Diencephalon controls which NS?
ANS
Information is relayed to which part of the CNS before it goes to the cerebral cortex?
Diencephalon
Diencephalon is considered the ___/____ ____ center
sensory/motor relay center
What are the three parts of the brain stem?
midbrain, pons, medula
The cranial nerve nuclei are located where?
In the three parts of the brain stem
What is in the brain stem?
cranial nerve nuclei
what function does the brain stem generate?
head and neck function
What part of the CNS generates head and neck function?
Brainstem
Where is the cerebellum located?
Behind the pons
Which part of the CNS coordinates movement?
Cerebellum
What does the Cerebellum do?
coordinate movement
Where is the spinal cord located?
beneath the medulla
Where does the spinal cord project to?
spinal column
Spinal cord consists of what matter?
grey and white matter
Reflexes are associated with which part of the CNS?
spinal cord
The meninges are made up of what type of tissue?
connextive tissue
What are the three maters of the meninges?
Dura mater, arachnoid mater, and pia mater
Dura mater is attached to what?
skull
Pia mater is attached to what?
brain
Which mater covers the cerebral vessels?
Pia mater
Why is it called arachnoid mater?
because of the spider-web processes that extend into the pia mater
Arachnoid mater lines what?
the inner dura surface
The faux cerebri consists of which 3 maters?
Arachnoid mater, dura mater, arachnoid mater
What is found between the skull and dura mater?
meningeal veins, arteries, and nerves