CMB Lecture 8 Flashcards

1
Q

What are point mutations?

A

Change in a single base pair

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2
Q

Types of point mutation:

A

Nucleotide pair substitutions, or pair insertions or deletions

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3
Q

Frameshifts are caused by:

A

Pair insertions or deletions

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4
Q

Pair substitutions are responsible for:

A

Silent, missense, nonsense mutations.

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5
Q

Silent mutations:

A

No effect on amino acid sequence

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6
Q

Missense mutations:

A

An amino acid is changed

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7
Q

Sickle cell disease is an example of:

A

Missense

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8
Q

Nonsense mutations:

A

Creation of termination codon.

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9
Q

Excision repair:

A

Repairing damaged DNA. Nuclease cuts the damaged DNA strand at two points and removes it.

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