CMB Lecture 8 Flashcards
1
Q
What are point mutations?
A
Change in a single base pair
2
Q
Types of point mutation:
A
Nucleotide pair substitutions, or pair insertions or deletions
3
Q
Frameshifts are caused by:
A
Pair insertions or deletions
4
Q
Pair substitutions are responsible for:
A
Silent, missense, nonsense mutations.
5
Q
Silent mutations:
A
No effect on amino acid sequence
6
Q
Missense mutations:
A
An amino acid is changed
7
Q
Sickle cell disease is an example of:
A
Missense
8
Q
Nonsense mutations:
A
Creation of termination codon.
9
Q
Excision repair:
A
Repairing damaged DNA. Nuclease cuts the damaged DNA strand at two points and removes it.
