Clostridium difficile Flashcards

1
Q

Classification bactériologique

A

Bacille GRAM +

Capacité de sporuler

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2
Q

Réservoir

A

Homme et nombreux animaux

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3
Q

Transmission

A

Par ingestion de spores

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4
Q

Facteurs de risque

A

Age > 65 ans
Hospitalisation
Antibiothérapie

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5
Q

Pouvoir pathogène

A
Diarrhée 
Colite pseudo-membraneuse 
Mégacôlon toxique 
Perforation colique 
Choc septique
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6
Q

Facteur de virulence

A

Toxines A et B

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7
Q

Diagnostic

A

Détection des toxines dans les selles ou d’une toxinogène
Ne fait pas partie de la coproculture standard
Endoscopie

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8
Q

Traitement

A
Réhydratation 
Arrêter l'antibiothérapie à risque 
Métronidazole per os 
Vancomycine per os 
Transplantation de microbiote fécal si récidives
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9
Q

Prévention

A

Attention aux antibiotiques

Précautions de contact

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