CLIPP 11 Flashcards

1
Q

main reason we tx strep throat (group a beta hemolytic strep typically)

A

to avoid rheumatic fever

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2
Q

rapid strep antigen test has __sensitiviyt and __specificty

A

variable, high

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3
Q

when to do strep culture

A

to confirm results of negative rapid strep

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4
Q

Appropriate antibiotics started within __ days from the start of the acute illness will prevent acute rheumatic fever.

A

9

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5
Q

Rx of choice in GAS infxn

A

PCN tho the liquid form tastes bad so amox is often used instead - ideally wait for documented +test before starting abx

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6
Q

3 of the many things that can present as irritablity

A

fatigue, meningitis, increased ICP/intracranial irritation

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7
Q

noraml 5yo HR

A

80-100

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8
Q

JIA can be broken into these different categories

A

polyarticular, pauci/oligoarticular, systemic-onset (stills dz)

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9
Q

Kawasaki dz is a form of __ w these sx

A

vasculiis.
non purulent conjunctiva, rash on body, arthraglia, strawberry tongue, hands and feet skin desquaamating . fever >5days. swelling and erythema of extremities.

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10
Q

one example of fever for >= 5 d

A

kawaki

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11
Q

osteomylitis / septic joint

A

low grade temp, pain walking if in lower extremities

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12
Q

rmsf

A

rash on palsm/soles/wrists that spreads inwards

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13
Q

rash on palms/soles

A

Kawasaki disease, enteroviruses, syphilis

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14
Q

scarlet fever

A

Fever (generally < 5 days) (whereas MORE duration in kawsaki)!
A diffuse, erythematous, finely papular rash (described as having a “sandpaper” texture) is pathognomonic
Rash often begins at neck, axillae, and groin and then spreads over trunk and extremities, typically resolving within four or five days

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15
Q

SJS

A

severe itchy rash (EM), fever <7d, mucosal changes, conjunctivitis. affects mucucutaneous things

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16
Q

viral syn/ antibiotisc

A

fever 3-5 d, non desecript NONPAINFUL rash that can start plams/soles,

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17
Q

does enterovirus rash hurt to walk

A

no

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18
Q

leggs calves pertches

A

ccurs when blood supply is temporarily interrupted to the ball part (femoral head) of the hip joint. Without sufficient blood flow, the bone begins to die — so it breaks more easily and heals poorly. would see limp but no rash, fever or conjunctivitis

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19
Q

conjuncitviits fever and rash

A

could mean measles or kawasaki. measles unlikely in fully immunzated kid

20
Q

can sinusitis cause rash?

21
Q

7 rashes assoc w/ fever and their distinguishing signs

A

enterovirus: often maculopapular, w high fever often, and often on palms/soles
erythema infectiousom: 5th dz/parvo, low fever–>rash 7-10d later w slapped cheek look and lacey and reticular on extremities. can cause arthralgia or aplastic anemia
measles: fever, cough, coryza, conjunctivitis–>rash at top of body–>spreads down to toes
meiningococcemia: due to NM. abrupt onset often w meningitis sx. can become purpuric.
roseola: fever–>fever goes–>rash on arms.neck often in kidsextremities/head. lesions of various stages. mild fever. dz is self limited, around a week.

22
Q

koplick spots

A

in measles, erythematous spots w/ bluewhite centers in buccal mucosa

23
Q

kawasaki mneuonic

A

CRASH and Burn
Conjunctivitis- non exudative, bilateral injection. >90%
Rash- anything….. but not vesicular and not bulla. >90%
Adenopathy > 1.5cm. typically cervical and unilateral. 90%
Hand- Swelling or Erythema or hands feet. progresses to peeling but this is late. >90%

and Burn… 5 days of daily fevers.

complications: coronary aneurisms.

Treatment is high dose aspirin(to prevent clots) and IVIG(reduces aneurisms from 20%-> 3%).

24
Q

is generalized LAD w or w/o splenomegaly more or less concerning than isolated LAD

25
infectious and non infectious causes of generalized LAD
histo, myco (local or isolated), toxo, hiv, measles, mono | leuk, lympho, metastatic neuro, rhabdo, histio
26
causes of unilateral cervical LAD
Bacterial cervical adenitis Cat scratch disease Reactive node from an oral inflammatory or infectious process Kawasaki disease Mycobacterial infection (both tuberculosis and atypical mycobacteria) can present with unilateral cervical lymphadenopathy, but the course of this illness is more indolent than Jason's
27
bacterial cervical adenitis
in younger children (1-5yo) after URI. often strep pyo or staph aureus. can have high fevers and look toxic and can get abscesses/celutlis
28
if kid has myobacterial lymphadenitis, most likely ___ in 2-4 yo children and __ in kids>12yo
non tuberculoous, tuberculousis
29
in PPD test, what do we measure? in normal people, what is a +result?
measure diameter NOT redness of induction. >=15mm
30
strawberry tongue w/ prominent pappilae
streptococcal pharyngitis (C), Kawasaki disease (E), and toxic shock syndrome (F).
31
kawasaki cbc
high wbc, normocytic normochromic anemia, normal mcv, normal plt until second week of dz where it rises
32
kawasaki lft
elevated, can have low albumin
33
elevated lfts in these two conditions w fever and rash, among others
sjs, kawasaki
34
kawasaki esr
neg esr would strongly argue against this
35
UA kawasaki
sterile pyruia - clea catch urine will show wbc while a cath urine won't since the wbc are from the urethra. sterile pyuria means +UA but -UC. leak esterase not as specific as #wbc.
36
kawasaki dx criteria
In addition to high fever for at least five days, four of the following five criteria are needed for a diagnosis of Kawasaki disease: ``` Changes in oral mucosa (A) Extremity changes (redness/swelling) (B) Unilateral cervical lymphadenopathy (C) Rash (D) Conjunctivitis (E) ``` The one least likely to be present is cervical adenopathy.
37
biggest complication in kawasaki
coronary artery aneurysm - do echo at acute phase to look for them and to make baseline, often the aneurysms are there by end of week 4.
38
general tx approach of kawasaki
echo, ekg, asrpiin (high dose 80-100mg/kg/day in 4 doses and then low dose after defervesence of 3-5mg/kg/day once for anti platelet effect and discontinue after 6-8 weeks if no aneurysm seen, but continue if seen aneurysm for anti platelet nature), iviv (helped decrease coronary aneurysm incidence and is given in single dose of 2g/kg over 10-12h)
39
aspirin in kawasaki does..
not help aneurysm dvpt control. helps fever and anti platelet
40
med to avoid in kawasaki and why
ibuprofen - antgaonizes aspirins anti platelet effect
41
f/u for kawasaki (4 things)
- w/ cardiology in 1-2 weeks bc if they are gonna have an aneurysm, its often within 4 weeks of acute illness - 6-8w of low aspirin so check for GI bleeds, Reyes and get flu shot - can have NSAIDS if arhtraglias are bad - monitor for fever
42
issue w/ aspirin in kids
reyes syndrome (multi organ failure) if get certain viruses while on aspirin. thus docs should make sure kid has flu shot /chiekn pox shot etc before staring aspirin .
43
cocksackie A is __
enterovirus
44
is there dysuria in kawasaki?
no - there is pyuria but dsyuria is related to UTI
45
systemic onset JIA
also known as Still’s disease, is a subset of JIA describing patients with intermittent rash, fever and arthritis. While our patient does present with rash and fever, as well as refusal to walk (potentially a sign of arthritis), systemic onset JIA tends to present with a history of spiking fevers and “salmon” rash occurring when the child is febrile, and disappearing as the fever fades.
46
two key modalities for JIA patients to f/u w.
optho (uveirits) and PT
47
one key modality for SJS pt to f/u w/
optho