Clinical- Remaining stuff Flashcards
What is the gram stain of H. Pylori?
negative
What is the shape of H. Pylori?
spiral bacillus
This type of chronic gastritis is caused by H. Pylori only, not by autoimmune diseases or chemical injury.
Type B chronic gastritis
AKA “active chronic gastritis”
What % of pts with duodenal ulcers have H. Pylori?
80%
If you don’t treat H. Pylori, the pt relapses how quickly into the infection?
1 yr
What % of gastric ulcers have H. Pylori?
50%
How can H. Pylori infections lead to adenocarcinomas?
piece it all together meow
H. Pylori infection –> chronic gastritis –> atrophic gastritis –> metaplasia –> dysplasia –> adenocarcinoma
H. Pylori induces the formation of what type of tumor on the MALT tissue?
B-cell lymphoma
True or False: a good way to help speed up the recovery process of non-ulcer dyspepsia, a physician should treat H. Pylori to allow the mucosa to heal faster.
FALSE. H. Pylori eradication doesnt help.
Why is serology such a good test for H. Pylori?
it’s cheap, nonivasive and has a 90-95% sensitivity
Why is serology sometimes inaccurate?
it remains + over time
PPI’s, antibiotics, or bismuth may give a false negative on what test for H. Pylori?
urease breath test
Scenario: you’re a doc and a tard 3rd year medical student says to you “uhhhhhh, mr. doctor sir? yeah, well, uhhhhh we did the test for that uhhhhh bug uhhhh H. Pylori and it came out +” You ask which test they did and he doesnt remember. What are the 2 options that could be the result of the + test for H. Pylori?
- it’s a + test from a urease breath test = infection
2. it’s a + test from a serology test = possible current OR past infection.
What is the combo therapy for H. Pylori treatment?
antisecretory agent + antimicrobial agent
What is the triple therapy used in the initial treatment of H. Pylori?
PPI + amoxicillin + clarithromycin
“PAC man”
for 10-14 days
