Clinical Features of COPD Flashcards
What is the clinical definition of COPD?
Chronic, slowly progressive disorder characterised by airflow obstruction that does not change markedly over several months. Lung function impairment is fixed
What is the prevalence of COPD in the UK?
1.2 million diagnosed - total prevalence is approximately 1.5-2 million
Which sex is typically more likely to develop COPD?
Men
What is the mortality rate of COPD?
6th most common cause of death in UK
30,000 deaths per year
What is the leading cause of COPD?
Smoking (comprises 85% of aetiologies)
What components make up the other 15% of causes of COPD?
Chronic asthma Passive smoking Maternal smoking Air pollution Occupation Alpha-1 antitrypsin deficiency
What is the rate of FEV1 decline in smokers and non-smokers respectively?
Smokers - 50-80ml/year
Non-smokers - 30ml/year
What are the differential diagnoses for COPD?
COPD Asthma Lung Cancer Left ventricular failure Fibrosing alveolitis Brochioectasis Rarities: TB recurrent pulmonary emboli
What are signs of severe COPD?
Weight loss and peripheral oedema
