Clinical correlates/notes from lecture Flashcards
sensory nervous system
afferent information conveyed from receptors in the periphery to the CNS
Motor nervous system
efferent information conveyed from the CNS to the skeletal, smooth and cardiac muscle
Somatic
body surface and musculoskeletal structures
Visceral
vessels, glands or organs containing smooth or cardiac muscle (ANS)
Efferent systems
Motor systems:
1) anatomically distinct sets of neurons
2) somatic is innervation of skeletal muscle
3) autonomic (Visceral) relates to innervation of smooth or cardiac muscle
Afferent systems
Sensory system
1) characterized by automically overlapping sets of neurons
2) somatic sensations are well localized
3) visceral sensations are poorly localized
LMN
have cell body in CNS and axon in PNS to innervate muscle fibers
Primary sensory neurons
have cell body in PNS with proximal process axon in CNS and distal process in PNS
Glia
the supportive cells
1) astrocytes in CNS
2) oligodendrocytes in CNS
3) microglia in CNS
4) Schwann cells in PNS
what are oligodendrocytes
Glia in CNS
myelin forming cells of the CNS
what are schwann cells
myelin forming cells of the PNS
Layers of the meninges
(closest to spinal cord) 1) pia mater
2) arachnoid matter (and subarachnoid space (CSF)
3) Dura Mater (underneath is potentail subdural space)
4) Epidural space for fat and veins
5) vertebra
Where are primary sensory neurons located in spinal cord?
Dorsal root (not cell bodies though)
What is the collect of PSC bodies located
Dorsal root ganglion
What is a spinal nerve?
combination of lower motor nuerons and primary sensory neurons.
what is the blood supply for the spinal cord?
Radicular arteries
Flexor withdrawal reflex
1) touch stimuli with primary sensory neuron
2) signal travels back to dorsal horn of spinal column
3) signal transfers to internuron that connects PSN to LMN in ventral horn
4) the LMN innervates the biceps to flex and withdraw hand
Fascicle
bundle of fibers by connective tissue
Epineurium
thick connective tissue that encloses the fascicles of the nerve
Endoneurium
delicates connective tissue the surrounds the nuerilemma cells
Perineurium
dense connective tissues that surround the axons of a single fasiicle. formed by flattened fiberglass like structures that act as a good barrier; tight junctions
what do the perinureim and epienurim form
a root sheath, or continuous barrier to the nerve bundles
what surrounds the ventral root in real life?
the dorsal root ganglion
Meningitis - possible diagnosis
patient refuses to raise leg
why is painful leg raising sign of meningitis?
raise leg you are stretching the sciatic nerve and also the epirnuerium and dura mater. you are tugging the dura matar. And in meningitis, the dura matar is inflamed.
The developing spinal cord
spinal cord is same length as developing vertebrate.
but when fetus grows, vertebrate grows and spinal cord stays same length. thus there is a relative downward displacement of the nerves
What would damage at L2 do?
damage all nerves inferior to L2, but not L2 itself
white vs grey matter
depends on the number of neurons. increased neurons = increased white matter.
white matter increases from sacral to cervial
Grey matter increases in the areas where there are extremities. (cervial and lumbar)
dermatome
area of skin innervated by a single spinal nerve
t4 dermatome
Nipple
t10
level of umblicus
Shingles
herpes virus, blood borm. infects skin and primary sensory neruons
transported by axoplastic transport to various areas of the skin, thus only certain segments appear and banded infections appear
Gray matter
Cell bodies
White matter
extended myelinated fibers
Cervical enlargement
C3-T2
lumbar enlargment
L1-S2
Spinal cord developent
neural plate (epidermis) flows and grows into a tube and gives rise to spinal cord and brain.
What do nueral crest cells give rise to?
primary sensory nuerons and schwann cells
If there is damage in dermatome (DRG), what would you expend in upper arm?
sensory loss along that single dermatome
If there is damage in periphery, what would you expect in upper arm?
if there is damage to both medial and lateral side of the skin. thus it is not damage to spinal cord.
sensory cutaenous field
when an area of skin is innervated by a single peripheral nerve, ie. lateral cutaneous femoral, which has nerve roots from multiple spinal levels.
myotome
the unilateral muscle mass receiving innervation from the fibers conveyed by a single spinal nerve
stretch reflex
hitting the tendon, stretches the tendon, muscle and spindle. Monosynpatic
1) this pulls the receptors springlike attachment appart and sends signal through primary sensory neuron through dorsal horn to ventral horn
3) synapases with lower motor neuron in ventral horn
4) signal transmits to bichep and causes muscle contraction
Calcaneal tendon spinal location
S1-2
Patellar tendon spinal location
L3-4
Biceps tendon spinal location
C5-6
Triceps tendon spinal locations
C7-8
Joint innervation
muscle or tendon crosses a joing, then the nerve that innervates the muscle also innervates the joint