Clinical Chemistry Flashcards
What sample type of used majority of the time in chemistry
Serum or plasma
What protein is found in plasma but not serum
Fibrinogen
Inert silicone gel is used as a barrier and what to type?
Separator tubes
What is the silicone separating
It is separating serum & plasma
True or false plasma separator tubes must be allowed to clock for 10 to 15 minutes before centrifugation
False
How long should a sample contain with serum separator to be allowed to clot
10-15 minutes
What are the centrifugation requirements for chemistry samples collected in an SST
3500 RPM at 5 to 10 minutes
How soon after collections of chemistry analysis ideally be completed
Within an hour
True or false the lower the temperature of perspiration the greater the stability of the chemical constituents
True
In regards to chemistry samples at what temperature is bacterial growth inhibited
4°C
In regards to chemistry samples at what temperature is bacterial growth completely stop
-5°C
At what temperature must samples be for chemistry
Room temp
Hemolyzed specimen
Serum appears clear read indicates red blood cells have ruptured
Icteric specimen
Serum is brownish yellow or vivid yellow indicates hepatitis or early liver diseases
Lipemic specimen
Serum is milky white color indicate the presence of lipids
Hemolysis causes false elevations to what chemistry analyses
Potassium acid phosphate lactate dehydrogenase and Aspirate aminotransferase
True or false actions of drugs can alter the concentration of substances being measured in chemistry drugs can also alter the chemical analysis directly
True
Where is the Preferred preservative for glucose testing
Sodium fluoride
What special handling requirement is needed for Billy Rubin analysis
Shields from light test immediately
What chemistry analytes are affected by moderate exercise
Glucose creatinine and the activity of skeletal enzymes AST CK & LD
Physical and chemical properties of what can directly all to the chemical analysis
Drugs
What type of interference can happen when there’s a hemolyzed enteric or lipemic specimen
Interference with photometric readings
True or false cortisol will decrease 50% from 800 to 16:00
False
What kind of specimen requires to be mix well prior to testing
Urine
What should shipping paperwork include
All specimen being shipped
What needs to be between the primary and secondary containers when shipping a package
Absorbent material
What should be reviewed from the receiving lab to ensure proper packing materials are used
Review O I
What does IATA
International air transportation association
Who is required to be trying to ship packages and how often do they need to be trained for
All lab personnel every 24 months
Explain the different types of reagents and standards
Type 1 used in critical analysis
Type 2 minimum grade of water purity
Type 3 sufficient for washing dishes
What is recommended to be checked with new receipts a reagent lots
Compatibility with current procedure is an expiration date
True or false controls can be used to troubleshoot your quality controls fall out of range or when reagent lot number changes
False
What actions are taken when performing correct of actions
Repeat controls once makes new controls troubleshoot analyzers
Call customer support do not report patient results
What are
Homogeneous Mixtures of two or more substances
Normal solution
The number of Graham equivalent weights per 1000 mL of solution
Molar solution
The amount of solute in each 100 mL of solution
Percent solution
The number oh grandma like your weights per 1000 mL a solution
What is used to determine the concentration of an unknown solution
Titration formula
When using the titration formula how many factories will be known and how many will be alone
Three or known one is unknown
What are the three different classifications of biohazard Material for shipment
Infectious substances
Diagnostic substances
Biological substances