Cardiac Markers Flashcards
What layer of the heart contain the muscle fibers in cardiac markers it also regulates contraction and relaxation of the heart
Myocardium
What proteins are responsible for heart retraction
Tropinin & trypomyosin
What proteins are responsible for heart contractions
Myosin & actin
What part of the cardiac conduction system is located in the wall of the right atrium
Sinuatrial node
What part of the cardiac conduction system is located in the bottom right atrium
Atrioventricular Node
What is secreted to decrease nodal activity in for the heart rate
Acetylcholine
Describe the relationship between nodal activity and heart rate
Dec nodal activity = inc heart rate
Inc nodal activity = dec heart rate
INVERSE
Do you have one example for sudden lots of blood resulting in death of heart muscle
Blood clot blocking coronary artery
What heart state is a result of electrical instability? This often occurs as a result of heart muscle
Ventricular fibrillation
A heart in ventricular fibrillation can result in permanent brain damage and death can occur unless oxygenated blood is restored within how much time
Five minutes
True or false clinical symptoms and EKG can diagnose Miocardial Infarction
False
List some MI confirmation test
Myoglobin troponin CKMB ALT AST CK
What test are included in a cardiac markers panel
Myoglobin CKMB & tropinin-I
How soon after MI can myoglobin be detected
One hour post
How long after MI does myoglobin remain elevated
12 to 24 hours
What cardiac marker is the most specific for am I? Why?
Troponin I because it’s a muscle protein that is released during MI
How long after MI does CKMB be detected?
2-4 days
How soon after MI can CKMB be detected
2 hours post
How soon after M I can troponin I be detected
Three hours post
How long after MI does troponin I remain elevated?
4-10 days
What is the principal for troponin testing?
Monoclonal antibody test (EIA)
List the risk factors
Diabetes smoking high blood pressure plaque accumulation hereditary
List the preventative measures for MI
Exercise don’t smoke know your risk
What are the cardiac enzymes?
Lactate dehydrogenase LD
Aspartate Aminotransferase AST
Creatine Kinase CK
