Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Chemistry > Bilirubin > Flashcards

Bilirubin Flashcards

You may prefer our related Brainscape-certified flashcards:
Periodic Table flashcards Chemistry 101 flashcards AP® Chemistry flashcards Organic Chemistry 101 flashcards
1
Q

How much blood is processed through the liver East minute

A

1500 mL per minute

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the toxic pigment produced during RBC destruction ? What is it rapidly reduce to?

A

Biliverden and it is converted into free BiliRubin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Indirect Bilirubin

A

Toxic unconjugated free alcohol soluble only

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Direct Bilirubin

A

Bilirubin diglucuronide Conjugated non-toxic water and alcohol soluble

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What does deliver conjugate free BiliRubin with in order to make a non-toxic

A

Gluronic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What type of bilirubin Is soluble in water and plasma

A

Direct bilirubin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Conjugated bilirubin is excreted into the bile then into the small intestine where it is reduced by bacterial enzymatic action to form a group of colorless compounds known as

A

Urobilinogens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is urobilinogen reduce to removed through the feces

A

Stercobiligen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Chromogen

A

Stercobilinigen porphobilinigen urobilinigen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Pigment

A

Bilirubin stercobilin urobilin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What gives stool it’s characteristic brown color

A

Stercobilinogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What causes urine to darken upon standing

A

Urobilin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the term for when bilirubin in the blood exceeds the normal range greater than 2.0 mg/dL

A

Hyperbilirubinemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the term for yellowing of the tissues skin and eyes due to excessive bilirubin levels in the blood called icterus

A

Jaundice

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Increase destruction of red blood cells causes larger amounts of Bilirubin to be transported to the liver then can be excreted also causes increased levels of urobilinogen in urine and stool

A

Pre-hepatic jaundice

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Most commonly caused by hemolytic transfusion resulting in massive distraction of RBCs release of hemoglobin and increased levels of bilirubin

A

Pre-hepatic jaundice

17
Q

Hemolytic disease of the New Born

A

Pre-hepatic jaundice

18
Q

Inability of the liver to conjugate in exercise BiliRubin because of liver disease or abnormalities

A

Hepatic jaundice

19
Q

Hepatitis cirrohsis cancer and inherited metabolic defects in conjunction of bilirubin

A

Hepatic jaundice

20
Q

And obstruction of the excretory ducks that prevents the excretion of bilirubin Caused by mechanical obstruction by stones stricture or tumors

A

Post hepatic or obstructive jaundice

21
Q

What type of bilirubin are measured to detect and monitor jaundice

A

Total Bilirubin

22
Q

What type of bilirubin are useful in making differential diagnosis

A

Direct and indirect bilirubin

23
Q

What type of bilirubin is mostly present in neonatal jaundice

A

Unconjugated

24
Q

Why are you serum the specimen of choice for bilirubin determinations

A

The addition of alcohol in the Evelyn Malloy method can precipitate proteins from plasma that interfere with the subsequent analysis

25
Q

Why should hemolysis be avoided in bilirubin determination

A

It falsely depresses the bilirubin result in most Assays

26
Q

Why should samples for bilirubin determination to be protected from light

A

Bilirubin Is light sensitive and can be destroyed by both light and heat

27
Q

Reaction method one direct reaction where water soluble bilirubin and diazonium yield color corresponding only to the direct bilirubin fraction
2. Indirect reaction where alcohol is added to demonstrate the free water insoluble bilirubin

A

Van den Bergh Reaction

28
Q

The Diaz reaction is used to determine the direct bilirubin in water methanol is added in a concentration that does not cause precipitation and proteins permitting the diazotization of indirect bilirubin Red violet color is red spectrophotometerically

A

Evelyn Malloy Bilirubin Procedure

29
Q

Reaction at a strongly alkaline pH result in a blue color

A

Jensrassik- Grof procedure

30
Q

Bilirubin + diazonium salts yields azobilirunin has a red violet color

A

Ehrlich reaction

31
Q

Modification of the Evelyn Malloy procedure which results in moderately increased sensitivity we agents are different

A

Jendrassik-Grof procedure

32
Q

Also call the Diazo reaction. Measures direct bilirubin only

A

Ehrlich reaction

Chemistry (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions