Classic Lab 2 Flashcards
Heterophile antibodies
Infectious mononucleosis (EBV)
Hexagonal, double-pointed, needle-like crystals in bronchial secreations
Bronchial asthma (Charcot-Leyden crystals: eosinophilic granules)
High level of D-dimers
DVT, PE, DIC
Hilary lymphadenopathy, peripheral granulomatous lesion in middle or lower lung lobes (can calcify)
Ghon complex (Primary TB Mycobacterium bacilli)
“honecomb lung” on xray or CT
Interstitial pulmonary fibrosis
Hypercoaguability (leading to migrating DVTs and vasculitis)
Trousseau syndrome (adenocarcinoma of pancreas or lung)
Hypersegmended neutrophils
Megaloblastic anemia (B12 deficiency: neurologic symptoms; folate deficiency: no neurolgic symptoms)
Hypertension, hypokalemia, metabolic alkalosis
Conn syndrome
Hypochromic, microcytic anemia
Iron deficiency anemia, lead poisoning, thalassemia ( fetal hemoglobin sometimes present)
Increased AFP in amniotic fluid/maternal serum
Datting error, anecephaly, spina bifida (neural tube defects)
Increase uric acid levels
Gout, Lesch-Nyhan syndrome, tumor lysis syndrome, loop and thiazide diuretics
Intranuclear eosinophilic droplet-like bodies
Cowdry type A bodies (HSV or CMV)
Iron-containing nodules in alveolar septum
Ferruginous bodies (asbestosis: increase chance of mesothelioma)
Keratin pearls on skin biopsy
Squamous cell carcinoma
Large lysosomal phagocytes, immunodeficient
Chediak-Higashi disease (congenital failure of phagolysosome formation)
“lead pipe” appearance of colon on barium enema xray
Ulcerative colitis (loss of haustra)
Linear appearance of IgG deposition on glomerular basement membrane
Goodpasture syndrome
Low serum ceroplasmin
Wilson Disease (hepatolenticular degeneration)
“Lumpy bumpy” apperance of glomeruli on immunoflourescence
Poststreptococcal glomerulonephritis (immune complex deposition of IgG and C3b)
Lytic (hole punched) bone lesions on xray
Multiple myeloma
Mammary gland “blue domed” cyst
Fibrocytic change of breast
Monoclonal antibody spike
Multiple myeloma (IgG or A) Monoclononal gammopathy of undetermined significance (MGUS consequence of aging) Waldenstrom (M protein = IgM) macroglobinemia Primary amyloidosis
Mucin filled cell with peripheral nucleus
“Signet ring” = gastric carcinoma