Class 21 - Nervous System pt. 3 Flashcards

1
Q

Neural integration

A

The ability to process, store, and recall information and use it to make decisions.

Chemical synapses allow for decision-making but synaptic delay makes info travel slower

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2
Q

2 types of postsynaptic potentials produced by neurotransmitters

A
  1. Excitatory postsynaptic potential (EPSP) - Voltage change from the RMP toward threshold (usually Na+ into cell)
  2. Inhibitory postsynaptic potential (IPSP) - Voltage becomes more negative than it is at rest (Cl- entry or K+ exit)
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3
Q

____ determine the kind of postsynaptic potential a neurotransmitter activates

A

Receptors in the postsynaptic membrane

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4
Q

Summation

A

The process of adding up postsynaptic potentials and responding to their net effect, whether it be excitatory or inhibitory

Occurs in the trigger zone

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5
Q

Two ways EPSPs can be added to reach threshold

A
  1. Temporal summation - A single synapse generates EPSPs so quickly that each is generated before the previous one fades
    Allow EPSPs to add up and reach threshold
  2. Spatial summation - EPSPs from several different synapses add up to threshold at an axon hillock
    An example of facilitation, where one neuron enhances the effect of another
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6
Q

Presynaptic facilitation

A

When one presynaptic neuron enhances another. Increases

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7
Q

Presynaptic inhibition

A

When one presynaptic neuron suppresses another one
Reduces or halts unwanted transmission

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8
Q

Neural coding

A

Converting stimulus information into meaningful pattern of action potentials

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9
Q

Labeled line code

A

Mechanisms for transmitting qualitative info of the ** type of stimulus**.

Communicated based on which neurons fire (e.g. optic nerve firing interpreted as “light”)

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10
Q

Two ways quantitative info is encoded in the nervous system

A

Info about the ** intensity of a stimulus**

  1. Weak stimuli only activate “low threshold” neurons
  2. Strong stimuli also activate less sensitive “high threshold” neurons through recruitment

Weak stimuli cause neurons to fire action potentials at a slower rate, strong stimuli cause higher firing frequency

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11
Q

Neural pools, discharge zone, and facilitated zone

A

Functional groups of neurons. Each pool consists of thousands of interneurons concerned with a particular bodily function.

Discharge zone - Zone where the input neuron can act alone to make postsynaptic neurons fire

Facilitated zone - Zone where input neuron makes fewer, less powerful synapses. Can only stimulate targets with the assistance of other input neurons

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12
Q

Diverging vs. converging neural circuits

A
  1. Diverging circuit - One nerve fiber branches and synapses with several postsynaptic cells
  2. Converting circuit - Input from many different nerve fibers is funneled to one neuron/neural pool
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13
Q

Reverberating vs. parallel after-discharge neural circuits

A

Reverberating - Neurons stimulate each other in linear sequence but one or more of later cells restimulates the first cell to start the process over (e.g. breathing)

Parallel after-discharge - Input neuron diverges to stimulate several chains of neurons, and neurons chains converge on one or few output neurons with varying delays

After-discharge = continued firing after stimulus stops

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14
Q

Serial processing

A

Neurons and neural pool relay info along a pathway in a relatively simple linear fashion

Can only process one flow of info at a time; multitasking between similar activities doesn’t exist,

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15
Q

Parallel processing

A

Info is transmitted along diverging circuits through different pathways that act on it simultaneously, for different purposes

E.g. visual and auditory systems fire the same nerves

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16
Q

Memory trace (engram), synaptic plasticity, synaptic potentiation

A

Pathway of synapses through the brain; physical basis of memory

Synaptic plasticity - Ability of synapses to change

Synaptic potentiation - Process of making transmission easier

17
Q

3 types of memory

A
  1. Immediate memory - stays in thoughts for a few seconds. Allows sense of the present. May depend on reverberating circuits
  2. Short-term memory - Lasts from seconds to hours. Includes working memory. Synaptic facilitation may be involved in memory formation/recovery
  3. Long-term memory - Lasts up to a lifetime. Involves formation and remodeling of synapses and long-term potentiation
18
Q

Tetanic stimulation and post tetanic potentiation

A

Tetanic stimulation - Rapid arrival of repetitive signals at synapse

Post tetanic potentiation - Calcium level in axon terminal stays elevated, results in exceptionally large burst of neurotransmitter

19
Q

Explicit vs implicit memory

A

Explicit - Memories you can put into words. Requires effort to remember

Implicit - Reflexive or unconscious memory. Includes emotional and procedural memories

20
Q

Long-term depression

A

Low-frequency stimulation of a synapse results in low levels of intracellular Ca2+.

Activates calcium phospatases, which dephosphorylate synaptic proteins

Proteins degraded by proteasomes

21
Q

2 diseases related to the nervous system/memory decay

A
  1. Alzheimer’s disease - ACh and nerve growth factor deficiencies
  2. Parkinson’s disease - Progressive loss of motor function due to degeneration of dopamine-releasing neurons