Class #1 Flashcards
Leading cause death ca?
1-cancer
2-Heart
3-stoke
Leading cause death in underdev. countries?
1-INfectious diseases
2-INjury
3-cancer
Global mortality causes?
1-heart
2-Communicable, maternal, perinatal diseases
2- cancer
DALY?
Disability-Adjusted Life Years = one DALY = one year of full health lost
Highest healthy life expectancy?
1-Japan
2-Singapore
3-Switz.
7-Canada
Life expectancy increase?
Average time expected to live.
2,2 years every decade for past 100 years
Sx? Sign?
Something you feel
You can observe
Lesion?
Structural change in tissue caused by disease
Sequel?
Something that follows as a result of a disease process
Complication?
May or may not occur
Biopsy=
Tissue sampling
Histology vs Cytology
1- Branch of Dx pathology where tissue sample are observed to detect problem
2- Individual cells are studied and determined if they are normal or abnormal
Types of epithelium?
1-simple squamous 2-simple cuboidal 3-simple columnar 4-Transitional 5-Stratified squamous 6-Stratified cuboidal 7-pseudostratified culumnar
Ways cells adapt to stress?
1-Atrophy 2-Hypertrophy 3-Hyperplasia 4-Metaplasia 5-Dysplasia
heterophagy vs autophagy?
1- breaking down something external
2-INternal
2 major types of tissues?
1-epithelial: protective/secretory
2-Connective: Structural/contractile
Atrophy causes?
C and organelles get smaller:
- Decrease workload: musc
- Inadequate blood supply
- Inadequate hormonal stimulation
- Inadequate nutrient supply
Hypertrophy types?
- Physiological: exercise, uterus
- Pathological: cardiac failure
- Enzyme induction: in the smooth endo. reti. where we make enzy. if too much demand (Eg alcohol), increase enz level.
Hyperplasia types?
- NUmber of c increase
- Combination of hyperplasia and hypertrophy = uterus in pregnancy
- Pathological hyperplasia:
Metaplasia?
Changing from one cell type to another.
Eg. mucociliary cells in smokers
Protective advantage, but lose normal function.
Dysplasia?
If stress causing metaplasia for too long.
Cells are diff. sizes, nuclei diff, divide more rapidly.
Prelude to cancer.
Anaplasia?
Losing the morphological characteristics of mature cells.
This is cancer