Citric Acid Cycle - (German)

Question 1

What is the NET production of Glycolysis?

Answer 1

• 2 ATP
• 2 NADH
• 2 Pyruvate

Question 2

T o F: Erythrocytes ONLY way of cellular respiration is through citric acid cycle

Answer 2

FALSE: Only glycolysis BC no mitochondria….

Question 3

What is the MAJOR product of the pentose phosphate pathway, and WHY is it important?

Answer 3

NADPH - Important BC, necessary for creating free fatty acids

Question 4

3 main fates of Pyruvate?

Answer 4

1. Acetyl-CoA (Glycolisis + O2)
2. Lactate (sin O2)
3. Ethanol (Yeast + bacteria)

Question 5

What is necessary for anaerobic respiration to occur?

Answer 5

the regeneration of NAD+

Question 6

How is the mitochondria linked to apoptosis?

Answer 6

Cytochrome C (the main e- carrier in ETC ) is moved OUT of the mitochondria, so it can essentially no longer produce ATP & so cell dies.

Question 7

What converts Pyruvate into 2 Acetyl-CoA’s?

Answer 7

Pyruvate Dehydrogenase

CO2 & NADH are also biproducts

Question 8

What is the rate limiting step in the citric acid cycle?

Answer 8

Citrate synthetase or the availability of oxolacetate & Acetyl CoA

Question 9

What are the fates of Oxaloacetate?

Answer 9

• Citrate
• Phosphenolpyruvate
• Asparagine (nucleic acid)

Question 10

NADH & Flavoproteins are what?

Answer 10

Electron Transfers

Question 11

The 3 e- carriers are…

Answer 11

1. Ubiquinon
2. Cytochrome
3. Fe-sulfur proteins

Question 12

The Q cycle is….?

Answer 12

• Complex III in ETC

- Transfers e- to cytochrome C

Question 13

The last e- acceptor in ETC is…?

Answer 13

Oxygen

Question 14

How many ATP are produced per NADH…FADH2?

Answer 14

NADH: 2.5 ATP
FADH2: 1.5 ATP

Question 15

Where is the Malate Asparate shuttle found? G3P Shuttle?

Answer 15

Malate: Liver, kidney & Heart

G3P: Brain & Muscle

Question 16

2 conditions that favor ROS formation?

Answer 16

• Mitochondria lacks O2 or ADP

- Excess NADH