Cirrhosis Flashcards

1
Q

What?

A

severe, chronic, irreversible fibrosis of liver

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2
Q

Causes

A

Chronic alcohol use

Viral hepatitis

Metabolic liver disease ((hemochromatosis, nonalcoholic steatohepatitis)

Cholestatic liver disease (primary biliary cirrhosis)

Drugs (amiodarone, methotrexate)

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3
Q

Signs/symptoms

A

Fatigue

Weight loss

Jaundice

Ascites

Hepatomegaly or splenomegaly

Encephalopathy

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4
Q

Diagnosis

A

Signs/symptoms

Markers of hepatic function–> Albumin, INR

Hepatic imaging

Liver biopsy

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5
Q

Assess severity

A

Child-Pugh

MELD

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