Ascites Flashcards
1
Q
What?
A
Fluid accumulation in peritoneal space
2
Q
Pathophysiology
A
Increase pressure with portal HTN drive fluid into the peritoneal space and activates the RAAS pathway leading to fluid retention
3
Q
Signs/symptoms
A
Nausea
Abdominal pain and distention
Shortness of breath
4
Q
Non-pharm treatment
A
Sodium restriction < 2g/day
Liver transplant??
5
Q
First line treatment
A
Spironolactone + Furosemide
Initial: 100(S) ; 40 (F)
Max: 400 (S); 160 (F)
CANNOT USE IF AKI
6
Q
Second line treatment
A
Indication: Refractory ascites with diuretics, AKI
If > 5L removed–>ALBUMIN
Albumin 25% IV 6-8 g/L removed
AVOID NSAIDS