Circulatory System Flashcards
Blood flows in two main circuits
- Systemic circulation
* Pulmonary circulation
Blood vessels
artery
vein
capillaries
carries blood away from the heart
artery
carries blood toward the heart
vein
can take higher pressure
artery
Artery and Vein 3 layers (from lumen side)
Tunica interna
Tunica media
Tunica externa
- Endothelium
- Basement membrane
- Internal elastic lamina
Tunica interna
Has smooth muscle and elastic fibers
Tunica media
• Has elastic and collagen fibers
• Contains nerves and the vasa vasorum
• Anchors vessel to surrounding
tissue
Tunica externa
Artery
Elastic artery
Muscular artery
Arteriole
• Large caliber (e.g. aorta and its branches, pulmonary artery)
• Thin walls (1/10th of diameter)
• Thick tunica media with more abundant elastic fibers than smooth
muscles
• Expands during ventricular systole
• Elastic recoil of walls constricting lumen propel blood forward during
ventricular diastole
• Conducting artery
Elastic artery
• Medium-sized artery (e.g. brachial artery, radial artery, femoral artery,
specific organ arteries)
• Thick walls (3/4th of diameter )
• More abundant smooth muscles than elastic fibers (up to 40 layers of
smooth muscles), always in a partial state of contraction (vascular
tone)
• Readily vasoconstricts and vasodilates to regulate blood flow, low
recoil capability
• Distributing artery
Muscular artery
• Microscopic vessels which regulate blood flow into
capillary network
• Wall is 1⁄2 vessel diameter
• Tunica media has 1 -2 smooth muscle cell layers with
a precapillary sphincter at the metarteriole (most
distal region)-capillary junction
• Its small diameter and constriction of walls by smooth
muscle contraction increase resistance to blood flow
and decrease blood into capillaries
• Resistance artery
Arteriole
where artery and vein would meet.
Where oxigen, carbon dioxide, nutrition exchange location.
capillaries
Smallest of the blood vessels, measuring 5 - 10μm in diameter, connect arterioles and venules No tunica media and tunica externa Has a single
-cell wall, the endothelium,
enables the interchange of water, oxygen,
carbon dioxide, other nutrient and waste
chemical substances driven by hydrostatic and
colloid osmotic pressures inside the capillary
and surrounding tissues (cells and interstitial
space)
Exchange vessels
RBC (diam=8μm) need to fold a little to pass
single file thru the capillaries
capillaries
• Found near all the cells of the body
• Distribution dependent on the tissue’s metabolic
activity
• Higher metabolic activity (e.g. brain, muscles, liver,
kidneys, CNS), more oxygen and nutrient
requirements, the denser the capillary network vs.
lower metabolic activity tissues (e.g. tendons,
ligaments)
• Absent in epithelium, cartilage, lens and cornea
capillaries
damaged veins that leads to backflow
varicose veins/varices
backflows are prevented by
valves
varicose veins reason
incompetent venous valves
there is blood backflow
Can also be found in the
esophagus and anal canal
varicose veins/varices