Chronic/fungal pneumonia Flashcards
Causal organism in Valley fever/desert bumps
Coccidioides immitis
Infective form of coccidioides
Arthrospores
Diagnostic form of coccidioides in tissue
Thick-walled, non-budding, spherules with spores
Hypersensitivity of positive skin test for coccidioides
Type IV hypersensitivity
Pulmonary findings in acute coccidiomycosis
Consolidation - lobar, segmental, multifocal
Nodules
Calcification on healing lesions
Inflammatory responses to coccidiomycosis
Neutrophils initially
Chronic granulomatous in tissues
Eosinophils
Reaction type of erythema multiforme
Type IV hypersensitivity
Systemic manifestations of coccidiomycosis
Erythema multiforme
Erythema nodosum
Dissemination into bones
Serology test for coccidiomycosis
IgM and IgG complement fixation test
Treatment options for coccidiomycosis
Azoles
Amphotericin B
High risk groups for histoplasmosis
Immunocompromised
Anti-inflammatory therapy with TNF-alpha inhibitors
Immunologically naive individuals going to endemic areas
Infectious form of histoplasma
Tuberculate microconidia/spores
Tissue phase of histoplasma
Multiple yeast forms in macrophages
CXR findings in histoplasmosis
Multiple nodular infiltrates in bilateral lungs
Cavitary lesion
Enlarged hilar and mediastinal nodes
Popcorn calcification
Treatment for histoplasmosis
Itraconazole
Amphotericin B
