Antitussives and Mucolytics

Question 1

Long-acting topical nasal decongestant that acts directly as an alpha-1 and alpha-2 agonist

Answer 1

Oxymetazoline

Question 2

Faster acting nasal decongestant that acts as an alpha-1 and alpha-2 agonist

Answer 2

Xylometazoline

Question 3

Nasal decongestant that has both alpha and beta agonist properties

Answer 3

Pseudoephedrine

Question 4

Nasal spray that acts as a decongestant by post-synaptic alpha-receptor stimulation

Answer 4

Phenylephrine

Question 5

Opioid derivative that decreases sensitivity of cough receptors by depressing the medullary cough center

Answer 5

Dextromethorphan

Question 6

Cough suppressant that anesthetizes the stretch receptors

Answer 6

Benzonatate

Question 7

Mucolytic that opens disulfide bonds to reduce viscosity of mucus

Answer 7

N-acetylcysteine

Question 8

Mucolytic used in pneumonia and other chronic respiratory diseases

Answer 8

N-acetylcysteine

Question 9

Mucolytic that increases the volume and reduces viscosity of secretions in the trachea and bronchi

Answer 9

Guaifenesin

Question 10

Recombinant human deoxyribonuclease I that acts as a mucolytic. Used in treatment of CF

Answer 10

Dornase alfa

Question 11

Mutation in which Ivacaftor and Lumacaftor are effective

Answer 11

G551D

Question 12

Drugs for pulmonary HTN

Answer 12

Bosentan
Epoprostenol
Sildenafil

Question 13

Drugs for CF

Answer 13

Dornase alfa
Ivacaftor
Lumacaftor
Acetylcysteine

Question 14

ET-1 antagonist used for pulmonary HTN

Answer 14

Bosentan

Question 15

PGI analogue used for pulmonary HTN

Answer 15

Epoprostenol

Question 16

PDE5 antagonist used for pulmonary HTN

Answer 16

Sildenafil