Chp 16 - addl diseases/conditions/consideration Flashcards
From CDC, chronic diseases affect how many US adults
1 in two
Lipid parameters associated with CVD
Elevated LDL and total cholesterol
Low HDL
Elevated TGs
Chronic elevated TGs associated with….
endothelial dysfunction AND an independent risk factor for CVD
Primary lipoproteins are…
LDL - major carrier, 60-70% of cholesterol
VLDL - major carrier of TG, 10-15% of total chol
IDL - formed from the b’down of VLDL, similar to LDL
HDL - made in SI and LIV – 20-30% of chol – TRANSPORTS lipids to the liver for recycling and removal. INVERSELY correlated with CVD
Non-HDL - TOTAL chol MINUS HD —OR— sum of LDL, VLDL, and IDL; STRONGLY associated with CVD
LDL chol values - optimal & very high
HDL, low and high
Total cholesterol
<100, >/equal to 190
HDL Low = <40
HDL High = >/= to 60
TOTAL = desirable, <200
High = >/= 240
TG normal
High
Very high
<150
High = 200-499
Very High = >/= 500
Prevalence of high cholesterol (>/= 240)
28.5 million
11.9% US adults
Most likely secondary cause of elevated/high - for those genetically predisposed
Sedentary
Excessive saturated fat, cholesterol, and trans fats
Dietary recs for managing dyslipidemia…
Lower LDL – 5-6% calories from sat fat, LIMIT sweets, sugar sweetened bevs, red meats
Exercise and lipid issues - type of exercise best? Plus what other factor?
Aerobic exercise PLUS weight loss - significant improvement
Typical problems contributing to dyslipidemia..
Sedentary lifestyle PLUS excess sat and trans fats, and cholesterol
Cancer, referred to as…
collection of approx 200 related diseases characterized by uncontrolled spread & growth of abnormal cells
Classification of different cancers based on…
cell type from which they orginate
Prevalence…
one of the leading causes of morbidity and mortality worldwide
Three general phases of cancer survivorship…
1) tx and recovery
2) living after recovery - survivors dz free or have stable dz
3) advanced cancer and end of life
Causes of cancer..
1) environmental exposures
2) lifestyle practices
3) medical interventions
4) viral infections
5) genetic traits
6) gender
7) aging