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BI442—Immunology > Chp 1—Elements of the immune system > Flashcards

Chp 1—Elements of the immune system Flashcards

1
Q

calor

A

heat

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2
Q

dolor

A

pain

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3
Q

rubor

A

redness

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4
Q

tumor

A

swelling

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5
Q

function of cytokines on circulatory sys

A

changes properties of capillary endothelial cells (vasodilation, increased permeability)

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6
Q

most valuable division of immunity

A

innate

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7
Q

first cell in lineage

A

multipotential hematopoietic stem cell

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8
Q

hematopoietic stem cell gives rise to…

A

myeloid & lymphoid precursors

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9
Q

lymphoid precursors gives rise to…

A

lymphocytes & NK cells

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10
Q

myeloid precursor gives rise to…

A

megakaryocyte/erythroid progenitor & granulocyte-macrophage progenitor

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11
Q

myeloblast gives rise to…

A

basophils, neutrophils, eosinophils, monocytes

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12
Q

related to parasitic infection

A

eosinophils & basophils

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13
Q

function of mast cells

A

reside in tissues, mediate inflammation, cause smooth muscle contraction, respond to allergens

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14
Q

function of helper T cells

A

secrete cytokines - activate macrophages - activate B cells to become plasma cells

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15
Q

MCH1

A

absent on unhealthy cells, attracting NK cells

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16
Q

MCH1 function

A

absent on unhealthy cells, attracting NK cells

17
Q

primary lymphoid tissues

A

thymus
bone marrow

18
Q

secondary lymphoid tissues

A

nodes
spleen
GALT/MALT
thoracic duct
Peyers patches
tonsils/adenoids

19
Q

cortex of node includes…

A

outer B cell follicle & germinal center, and inner T cell area

20
Q

runs around outside of node

A

medullary sinus

21
Q

causes swollen nodes

A

swelling of B cell follicle during infection

22
Q

function of red pulp

A

degradation of RBCs

23
Q

function of white pulp

A

deals with pathogens in the blood

24
Q

central arteriole

A

area in white pulp where T cells interact with pathogens

25
Q

asplenia increases susceptibility to…

A

capsular bacteria
Strep pneumo

26
Q

function of M cells

A

form gateway between lumen and GALT/MALT

BI442—Immunology (8 decks)

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