Chp 1—Elements of the immune system Flashcards
calor
heat
dolor
pain
rubor
redness
tumor
swelling
function of cytokines on circulatory sys
changes properties of capillary endothelial cells (vasodilation, increased permeability)
most valuable division of immunity
innate
first cell in lineage
multipotential hematopoietic stem cell
hematopoietic stem cell gives rise to…
myeloid & lymphoid precursors
lymphoid precursors gives rise to…
lymphocytes & NK cells
myeloid precursor gives rise to…
megakaryocyte/erythroid progenitor & granulocyte-macrophage progenitor
myeloblast gives rise to…
basophils, neutrophils, eosinophils, monocytes
related to parasitic infection
eosinophils & basophils
function of mast cells
reside in tissues, mediate inflammation, cause smooth muscle contraction, respond to allergens
function of helper T cells
secrete cytokines - activate macrophages - activate B cells to become plasma cells
MCH1
absent on unhealthy cells, attracting NK cells
MCH1 function
absent on unhealthy cells, attracting NK cells
primary lymphoid tissues
thymus
bone marrow
secondary lymphoid tissues
nodes
spleen
GALT/MALT
thoracic duct
Peyers patches
tonsils/adenoids
cortex of node includes…
outer B cell follicle & germinal center, and inner T cell area
runs around outside of node
medullary sinus
causes swollen nodes
swelling of B cell follicle during infection
function of red pulp
degradation of RBCs
function of white pulp
deals with pathogens in the blood
central arteriole
area in white pulp where T cells interact with pathogens
asplenia increases susceptibility to…
capsular bacteria
Strep pneumo
function of M cells
form gateway between lumen and GALT/MALT
