Choosing an Abx

Question 1

Anti-MSSA (PO)

Answer 1

Gold: dicloxacillin
Silver: cephalexin

Other: minocycline/doxycycline, TMP-SMX, clindamycin

Question 2

Anti-MRSA (PO)

Answer 2

1. Linezolid/tedizolid
2. Minocycline/doxycycline
3. TMP-SMX
4. Clindamycin*
5. Delafloxacin

Question 3

Anti-Pseudomonal (PO)

Answer 3

Ciprofloxacin & Levofloxacin

Question 4

Anti-VRE (PO)

Answer 4

Linezolid/tedizolid

Question 5

Anti-Anaerobic (PO)

Answer 5

Gold: metronidazole or amox/clav
Silver: clindamycin

Question 6

Anti-MSSA (PAR)

Answer 6

Gold: nafcillin
Silver: cefazolin
Bronze: vancomycin

Question 7

Anti-MRSA (PAR)

Answer 7

Gold: vancomycin

Other: linezolid/tedizolid, daptomycin, tigecycline, telavancin/oritavancin/dalbavancin, ceftaroline, delafloxacin

Question 8

Anti-Pseudomonal (PAR)

Answer 8

1. pip/taz
2. aztreonam
3. ceftazidime/ceftolazone/cefepime
4. ciprofloxacin or levofloxacin
5. tobramycin
6. doripenem > meropenem > imipenem (not ertapenem)

Question 9

Anti-VRE (PAR)

Answer 9

1. linezolid/tedizolid
2. daptomycin
3. tigecycline
4. telavancin/oritavancin/dalbavancin

Question 10

Anti-Anaerobic (PAR)

Answer 10

Gold:

• b-lactam/b-lactamase inhibitor (amp/sul & pip/taz)
• carbapenems
• metronidazole

Silver: clindamycin