$$ AED Categories $$ Flashcards
1
Q
“Old” 1st Gen AED
A
- phenobarbital
- phenytoin
- carbamazepine
- valproate
- ethosuximide
2
Q
“New” 2nd Gen AED
A
- gabapentin
- pregabalin
- levetiracetam/brivaracetam
- lamotrigine
- oxcarbazepine/eslicarbazepine
- tiagabine
- topiramate
- zonisamide
- felbamate
- lacosamide
- rufinamide
- ezogabine
- vigabatrin
- perampanel
- BZDs (clobazam/clonazepam)
- cannabidiol
3
Q
Partial, including secondarily generalized seizures
A
Carbamazepine
Lamotrigine
Levetiracetam
Oxcarbazepine
4
Q
Primary generalized tonic-clonic seizures
A
Lamotrigine
Levetiracetam
Valproate
5
Q
Absence Seizures
A
Ethosuximide
Valproate
6
Q
Atypical Absence, Myoclonic, Atonic Seizures
A
Lamotrigine
Levetiracetam
Valproate
7
Q
Drugs that affect Na channels
A
- carbamazepine
- oxcarbazepine/eslicarbazepine
- phenytoin/fosphenytoin
- lamotrigine
- lacosamide
- zonisamide
- rufinamide
8
Q
Drugs that affect K channels
A
- ezogabine
9
Q
Drugs that affect Ca2+ channels
A
- ethosuximide
- gabapentin
- pregabalin
10
Q
Drugs that affect GABA activity
A
- phenobarbital
- clobazam
- clonazepam
- tiagabine
- vigabatrin
11
Q
Glutamate Receptor Antagonists
A
- perampanel
12
Q
Drugs w/multiple mechanisms of action
A
- valproate
- topiramate
13
Q
Drugs w/unknown mechanism of action
A
- felbamate
- levetiracetam
- brivaracetam
- cannabidiol
14
Q
AED that make absence or myoclonic seizures worse
A
- carbamazepine
- oxcarbazepine / eslicarbazepine
- gabapentin
15
Q
AED for LGS
A
- lamotrigine
- rufinamide
- clobazam
- clonazepam
- felbamate
- cannabidiol
- topiramate