Cholinergic Drugs and Use Flashcards by Zak Reneau | Brainscape

Q

What type of drug is Acetylcholine and what is it used for?

A

Direct-acting cholinergic agonist; Intraocular use during surgery causing miosis

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Q

What type of drug is Carbachol and what is it used for?

A

Direct-acting cholinergic agonist; Glaucoma Tx or miosis during surgery or ophthalmic exam

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Q

What type of drug is Bethanechol and what is it used for?

A

Direct-acting cholinergic agonist; Tx of urinary retention and heartburn; SE = UTI

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Q

What type of drug is Cevimeline and what is it used for?

A

Direct-acting cholinergic agonist; tablet for xerostomia Tx

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Q

What type of drug is Pilocarpine and what is it used for?

A

Direct-acting cholinergic agonist; Tx for xerostomia, xerostomia related head/neck cancer, miosis (topical), glaucoma (topical)

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Q

What type of drug is Edrophonium?

A

Charged, indirect-acting cholinergic agonist (AchE inhibitor)

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Q

What type of drug is Pyridostigmine?

A

Charged, indirect-acting cholinergic agonist (AchE inhibitor)

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Q

What type of drug is Neostigmine?

A

Charged, indirect-acting cholinergic agonist (AchE inhibitor)

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Q

What type of drug is Echothiophate?

A

Charged, indirect-acting cholinergic agonist (AchE inhibitor)

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Q

What type of drug is Ambenonium?

A

Charged, indirect-acting cholinergic agonist (AchE inhibitor)

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Q

What type of drug are Organophosphates?

A

Neutral, indirect-acting cholinergic agonist (AchE inhibitor)

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Q

What type of drug is Physostigmine?

A

Neutral, indirect-acting cholinergic agonist (AchE inhibitor)

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Q

What type of drug is Donepezil?

A

Neutral, indirect-acting cholinergic agonist (AchE inhibitor)

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Q

What type of drug is Galantamine?

A

Neutral, indirect-acting cholinergic agonist (AchE inhibitor)

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Q

What type of drug is Rivastigmine?

A

Neutral, indirect-acting cholinergic agonist (AchE inhibitor)

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Q

What type of drug is Tacrine?

A

Neutral, indirect-acting cholinergic agonist (AchE inhibitor)

Q

What is Varenicline used for?

A

Smoking cessation; partial agonist of nAchR’s

Q

What is Scopolamine used for?

A

Motion sickness

Q

What is Oxybutynin used for?

A

GU disorders

Q

What is Dicyclomine used for?

A

GI disorders

Q

What is Hyoxcyamine used for?

A

GI disorders

Q

What is Ipratropium used for?

A

Respiratory disorders

Q

What is Tiotropium used for?

A

Respiratory disorders

Q

What is the combination of Atropine + Pralidoxime used for?

A

Cholinergic poisoning

Q

What is Benztropine used for?

A

Parkinsons disease (reduce tremors)

Q

What is Trihexyphenidyl used for?

A

Parkinsons disease (reduce tremors)

Q

What is Procyclidine used for?

A

Parkinsons disease (reduce tremors)

Q

What is Lomotil used for?

A

GI disorders (mAchR antagonist for travelers diarrhea)

Q

What is Darifenacin used for?

A

GU disorders

Q

What is Solifenacin used for?

A

GU disorders

Q

What is Tolterodine used for?

A

GU disorders

Q

What are the SE of Oxybutynin?

A

Xerostomia, constipation, dizziness, blurred vision

Q

Why would you use Darifenacin, Solifenacine, or Tolterodine over Oxybutynin?

A

They have less xerostomia and constipation with a longer half-life