Cholinergic Antagonists / Blocking

Question 1

Cholinergic Antagonists / Blocking

Answer 1

• *SNS: flight/ flight

- vasoconstriction, increased HR, bronchodilation, pupils dilate, decreased motility, decreased GU

Question 2

Cholinergic Antagonists / Blocking: MOA

Answer 2

blocks cholinergic receptors, increases HR, ect.

Question 3

Cholinergic Antagonists / Blocking: Indications

Answer 3

bradycardia, excessive secretions, urinary frequency, IBS

Question 4

Cholinergic Antagonists / Blocking: Contraindications

Answer 4

glaucoma, asthma, GI/GU tract obstruction, CV disorders

Question 5

Cholinergic Antagonists / Blocking: AE’s

Answer 5

tachycardia, irritability, delirium, dilated pupils, decreased secretions, urinary retention

Question 6

Cholinergic Antagonists / Blocking: Interactions

Answer 6

additive / competitive, antihistamines, tricyclic antidepressants, digoxin

Question 7

Cholinergic Antagonists / Blocking: NC’s

Answer 7

VS, I & O, assessments

Question 8

dicyclomin

Answer 8

• MOA: dicyclomine is a cholinergic blocker that helps to reduce stimulation to the G.I. tract
• Indications: it is a drug that is used primarily to treat irritable bowel syndrome.
• Contra: allergy, glaucoma and any disorders of the G.I. tract, MS

AE’s: adverse effects that mimic CNS stimulation increased heart rates increase pressures and decreased separations

Question 9

atropine

Answer 9

MOA: Cholinergic Blocker

Indications: Bradycardia, Control Secretions (Oral, Airway & GI)

Contraindications: Allergy, Glaucoma, Asthma, Liver & Renal Dysfuncion, GI & GU obstruction

Adverse Effects: See Following Slide

Interactions: Antacids, Anticholinergics, Levodopa

Nursing Considerations: I&O, Teaching about adverse effects

Question 10

oxybutnin

Answer 10

MOA: Antimuscarinic/Anticholinergic/Cholinergic Blocker
Indications: Overactive Bladder

Contraindications: Allergy, Urinary & Gastric Retention, Uncontrolled Glaucoma

Adverse Effects: CNS Stimulation, Tachycardia, Urine

Retention, Dec. GI Motility

Interactions: Anticholinergics, Beta Blockers, CNS Depressants

Nursing Considerations: Pt. History, Check for residual urine after voiding