Chemotherapeutic Drugs (Bacterial, Viral, Fungal) Flashcards
(37 cards)
What antibiotics are bactericidal?
BACTERICIDAL ANTIBIOTICS Very Finely Proficient At Murder! Vancomycin Fluoroquinolones Penicillins Aminoglycosides Metronidazole
What antibiotics are bacteriostatic?
BACTERIOSTATIC ANTIBIOTICS We're ECSTaTiC about bacteriostatics Erythromycin Clindamycin Sulfamethprim Trimethoprim Tetracycline Chloramphenicol
Mnemonics-Routes of Administration of Penicillins
Pen V is Oral, ipapasok sa Vunganga
Pen G is IV: You inGect Pen G
Mnemonics-Nafcillin
Use naf (nafcillin) for staph.
Mnemonics-Ampicillin/Amoxicillin
AMPicillin = AMPed up penicillin amOxicillin = greater Oral bioavailability
Describe the antimicrobial coverage of extended spectrum penicillins.
Amoxicillin HELPS kill Enterocci Haemophilus influenzae Escherichia coli Listeria monocytogenes Proteus mirabilis Salmonella spp. Enterococci
Mnemonics-Antipseudomonal Penicillins
TCP: Takes Care of Pseudomonas
Ticarcillin
Carbenicillin
Piperacillin
Which microbes are covered by the spectrum of activity of first generation cephalosporins?
FIRST GENERATION CEPHALOSORINS PEcKs FIRST Proteus mirabilis Escherichia coli Klebsiella pneumoniae
How do you remember first generation cephalosporins?
FIRST GENERATION CEPHALOSPORINS FADer, help me FAZ my PHarmacology boards! CeFADroxil CeFAZolin CePHalothin CePHapirin CePHradine CePHalexin
Which microbes are covered by spectrum of activity of second generation cephalosporins?
SECOND GENERATION CEPHALOSORINS HEN PEcKS Haemophilus influenzae Enterobacter aerogenes Neisseria spp. Proteus mirabilis Escherichia coli Klebsiella pneumoniae Serratia marcescens
How do you remember second generation cephalosporins?
SECOND GENERATION CEPHALOSPORINS
In a FAMily gathering, you see your FOXy cousin wearing a FUR coat and drinking TEA.
CeFAMandole, CeFOXitin
CeFURoxime, CefoTEtan
SECOND GENERATION CEPHALOSPORINS
FAC! LORA the PROfessional AZhOLE is still on the FONe.
CeFAClor, LORAcarbef, CefPROzil, CefmetAZOLE, CeFONicid
How do you remember third generation cephalosporins?
THIRD GENERATION CEPHALOSPORINS FEnge PO ng PERA to FIX my TTTTTV! CeFEtamet CefPOdoxin CefoPERAzone CeFIXime CefTriaxone CefTazidime CefoTaxime CefTizoxime CefTibuten
Which cephalosporins are anti-pseudomonal?
ANTI_PSEUDOMONAL CEPHALOSPORINS
CefTAZidime
CeFEPime
CeFOPerazone
Mnemonics-Imipenem Cilastatin
With Imipenem, the kill is LASTIN with ciLASTatIN.
Which antibiotics are considered drugs of last resort?
I AM your Last Shot at Victory Imipenem Amikacin Meropenem Linezolid Streptogramins Vancomycin
Mnemonic - Protein Synthesis Inhibitors
BUY AT 30, CELLS AT 50 A=Aminoglycosides T=Tetracyclines C=Chloramphenicol E=Erythromycin (Macrolides) L=Lincosamides (Clindamycin) L=Linezolid S=Streptogramins
Mnemonics-Tetracycline
T=TeTracyclines = Block aTTachment of T-RNA to acceptor site
Mnemonics-Clindamycin VS Metronidazole
CLINDAMYCIN for anaerobic infections ABOVE the diaphragm.
METRONIDAZOLE for anaerobic infections BELOW the diaphragm.
Mnemonics-Aminoglycosides
AminOglycosides require O2 for transport. They won’t work under anaerobic conditions.
Mnemonics-Aminoglycosides
Mean GNATS canNOT kill anaerobes. Gentamicin Neomycin Amikacin Tobramycin Streptomycin
Nephrotoxicity
Ototoxicity
Teratogen
Mnemonics-Fluoroquinolones
FloroquinoLONES hurt attachment to your BONES (cartilage damage)
Mnemonics-Isoniazid
INH Injures Neurons and Hepatocytes
Mnemonics-Rifampicin
R=Rifampicin RNA Polymerase inhibitor Red-orange body fluids Rapid development of resistance Revs up cytochrome P450 (inducer)
Which anti-TB drugs are hepatotoxic?
ISO a Red PYRe!
( I saw a red fire!)
Isoniazid < Rifampin < Pyrazinamide
