Charcot Marie Tooth Disease

Question 1

Charcot Marie tooth disease is an autosomal___ disease that affects the __ sensory and motor neurones, due to dysfunction in the __ or the __ themselves

Answer 1

Dominant

Peripheral

Myelin

Axons

Question 2

What are some classical signs and symptoms in Charcot Marie tooth disease? (Any 4, must have first 3 on list)

Answer 2

High foot arches (pes cavus)

Distal muscle wasting causing inverted champagne bottle legs

Weakness in ankle dorsiflexion

Weakness of hands

LMN signs

Peripheral sensory loss

Question 3

Causes of peripheral neuropathy? (5)

Answer 3

ABCDE

A-Alcohol 
B-B12 deficiency 
C-Cancer and Chronic kidney disease 
D-Diabetes and Drugs (isoniazid, amioderone, cisplastin)
E-Every vasculitis