Characterizing Antibodies (GAMED)

Question 1

The 2 main antibodies involved in antibody-mediated immunity. Secreted by activated B (plasma) cells to bind to invading antigens

Answer 1

IgG and IgM

Question 2

“first-line,” localized, defense in mucosal fluids (saliva, sweat, mucous, breast milk, GI secretions)

Answer 2

IgA

Question 3

the antibodies embedded in the B-cell membrane, which makes them BCR

Answer 3

IgD

Question 4

“first-lin,” localized, defense, located in mast cells and basophils in mucosal structures. They bind like allergens and induce huge inflammatory responses by release of cytokines (histamine, prostaglandins, leukotrienes, bradykinin)

Answer 4

IgE

Question 5

It can be in pentameric form

Answer 5

IgM

Question 6

Typically exist only as monomers

Answer 6

IgG, IgE, IgD

Question 7

It can be in dimeric form

Answer 7

IgA

Question 8

Which 2 are transferable to an offspring

Answer 8

IgG moves across the placenta to the fetus

IgA found in breast milk

Both confer “passive immunity”