Chapters 41-43, 45 Drugs

Question 1

Acyclovir

Answer 1

Antiviral used for the treatment of viral infections, chickenpox, shingles and herpes; completely inhibits and inactivates HSV-specified DNA polymerases preventing further viral DNA synthesis

Question 2

Amantadine

Answer 2

Antiviral and antiparkinsonian medication

Question 3

Amoxicillin

Answer 3

Antibiotic for bacterial infections

Question 4

Chloroquine

Answer 4

Treatment of malaria; enters the red blood cell, inhibits parasite cell and digestive vacuole by simple diffusion

Question 5

Ciprofloxacin

Answer 5

Antibiotic for bacterial infections; inhibits DNA gyrase and topoisomerase IV, which inhibits cell division

Question 6

Doxycycline

Answer 6

Antibiotic used for pneumonia, acne, chlamydia, Lyme disease, cholera and syphilis; used to prevent malaria; prevents binding of tRNA to mRNA at the ribosomal subunit

Question 7

Doxorubicin

Answer 7

Chemotherapy medication used to treat cancer; inhibits the progression of topoisomerase II, an enzyme which relaxes supercoils in RNA for transcription

Question 8

Erythromycin

Answer 8

Antibiotic for respiratory tract infections, skin infections, chlamydia, syphilis, etc.

Question 9

Fluconazole

Answer 9

Antifungal drug used to treat Candida

Question 10

Gentamicin

Answer 10

Antibiotic for bone infections, endocarditis, meningitis, pneumonia, UTI, sepsis, etc; binds to the 30S subunit of bacterial ribosome, negatively impacting protein synthesis

Question 11

Leuprolide

Answer 11

Manufactured version of a hormone to treat prostate cancer, breast cancer, endometriosis; agonist of pituitary GnRH receptors

Question 12

Metronidazole

Answer 12

Antibiotic and antiprotozoal medication to treat pelvic inflammatory disease, endocarditis, bacterial vaginosis

Question 13

Neomycin

Answer 13

Aminoglycoside antibiotic found in many topical meds

Question 14

Nystatin

Answer 14

Antifungal medication used for vaginal yeast infections, diaper rash, etc.; ionophore that binds to ergosterol

Question 15

Quinine

Answer 15

Treatment of malaria; theorized to be toxic to the malarial pathogen

Question 16

Ribavirin

Answer 16

Antiviral for RSV infection, hepatitis C, and viral hemorrhagic fever; guanosine analog used to stop viral RNA synthesis and viral mRNA capping

Question 17

Saquinavir

Answer 17

Antiretroviral for AIDS/HIV; protease inhibitor

Question 18

Streptomycin

Answer 18

Antibiotic for tuberculosis, endocarditis, plague, etc.; protein synthesis inhibitor

Question 19

Sulfamethoxazole

Answer 19

Antibiotic for UTIs, bronchitis, and prostatitis

Question 20

Sulfasalazine

Answer 20

Medication for rheumatoid arthritis, ulcerative colitis, and Crohn’s disease

Question 21

Tamoxifen

Answer 21

Prevent and treat breast cancer and Albright syndrome

Question 22

Vancomycin

Answer 22

Antibiotic used for skin infections, blood infections, endocarditis, meningitis, etc.; inhibits proper cell wall synthesis in gram-positive bacteria

Question 23

Zidovudine

Answer 23

Antiretroviral used to prevent and treat HIV/AIDS; thymidine analogue; selectively inhibits HIV’s reverse transcriptase