Chapter Two: Chemistry Flashcards
Produce more energy than they use
release energy
Exergonic [exothermic] reactions
Essential molecules obtained from food
Nutrients
Use more energy than they produce
absorb energy
Endergonic [endothermic] reactions
Molecules made or broken down in the body
Metabolites
Molecules not based on carbon and hydrogen
Inorganic compounds
Molecules based on carbon and hydrogen
Organic compounds
Inorganic compounds:
Carbon dioxide, oxygen, water and inorganic acids, bases, and salts
Organic compounds:
Carbohydrates, proteins, lipids and nucleic acids
Accounts for 2/3 of your total body weight
Water
A uniform mixture if two of more substances
Solution
The medium where atoms, ions or molecules are individually dispersed
Solvent
dispersed substances
Solute
A solutions ability to dissolve a solute in a solvent to make a solution
Solubility
the most abundant and functionally important organic molecules
proteins
proteins contain which basic elements?
carbon, hydrogen, oxygen and nitrogen
basic building blocks of proteins
20 amino acids
seven major protein functions
- support
- movement
- transport
- buffering
- metabolic regulation
- coordination and control
- defense
protein structure is made of
long chains of amino acids
five components of amino acid structure
- central carbon atom
- hydrogen atom
- amino group [-NH3]
- carboxyl group [-COOH]
- variable side chain or r group
R group determines
the reactivity and chemical structure of the protein
basic building blocks of proteins
20 amino acids
seven major protein functions
- support
- movement
- transport
- buffering
- metabolic regulation
- coordination and control
- defense
protein structure is made of
long chains of amino acids
five components of amino acid structure
- central carbon atom
- hydrogen atom
- amino group [-NH3]
- carboxyl group [-COOH]
- variable side chain or r group
R group determines
the reactivity and chemical structure of the protein
primary structure of a protein
the sequence of amino acids along a polypeptide
pyrimidines
cytosine, thymine and uracil
tertiary structure of a protein
secondary structure folds into a unique shape
quaternary structure of a protein
final protein shape. some are tertiary structures linked together like hemoglobin
the chemical bond formed between two molecules when the carboxyl group of one molecule reacts with the amino group of the other molecule due to the release of a molecule of water
peptide bond
chain of amino acids linked by peptide bonds
peptide
mis-folding proteins that cause disease
- Tau protein in Alhimerz’s Disease
2. Prion in CJD/Mad Cow Disease
structural sheets or strands commonly found in fibers structures in the body
fibrous proteins
soluble spheres with active functions and the protein function is based on shape ex: transport protein
globular proteins
the shape of a protein is based on
the sequence of amino acids
enzymes are
catalysts
lower the activation energy of a chemical reaction and do not change or are used up in a reaction
catalysts
an ion or molecule that binds to an enzyme before substrates can bind
cofactor
nonprotein organic cofactors [vitamins]
coenzyme
two enzymes that can catalyze the same reaction
isozymes
loss of shape and function due to heat or pH
denaturation
large protein + small carbohydrate that includes enzymes, antibodies, hormones and mucus production
glycoproteins
large polysaccharides + polypeptides that promote viscosity
proteoglycans
are large organic molecules, found in the nucleus, which store and process information at the molecular level
nucleic acids
functions of deoxyribonucleic acid [DNA]
- determines inherited characteristics
- directs protein synthesis
- controls enzyme production
- controls metabolism
function of ribonucleic acid [RNA]
controls intermediate steps in the protein synthesis
the building blocks of DNA and RNA
Nucleotides
molecular parts of nucleotides
- pentose sugar [deoxyribose or ribose]
- phosphate group
- nitrogenous base [A, G, T, C, U]
purines
adenine and guanine
pyrimidines
cytosine, thymine and uracil
adding a phosphate group to ADP with a high energy bond to form the high energy compound ATP
phosphorylation
enzyme that catalyzes the conversion of ATP to ADP
adenosine triphosphatase [ATPase]
proteins contain which basic elements?
carbon, hydrogen, oxygen and nitrogen
the most abundant and functionally important organic molecules
proteins
proteins contain which basic elements?
carbon, hydrogen, oxygen and nitrogen
basic building blocks of proteins
20 amino acids
seven major protein functions
- support
- movement
- transport
- buffering
- metabolic regulation
- coordination and control
- defense
protein structure is made of
long chains of amino acids
five components of amino acid structure
- central carbon atom
- hydrogen atom
- amino group [-NH3]
- carboxyl group [-COOH]
- variable side chain or r group
R group determines
the reactivity and chemical structure of the protein
primary structure of a protein
the sequence of amino acids along a polypeptide
secondary structure of a protein
hydrogen bonds form spirals or pleats
tertiary structure of a protein
secondary structure folds into a unique shape
quaternary structure of a protein
final protein shape. some are tertiary structures linked together like hemoglobin