Chapter Seven FIBER Flashcards

1
Q

What is a fixed idea according to Atle Selberg?

A

A fixed idea is dangerous as it leads a person to always find a way to convince themselves that they are right.

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2
Q

What significant event regarding sugar and refined carbohydrates occurred in April 1973?

A

The Senate Select Committee on Nutrition and Human Needs held its first hearing on diet and chronic diseases.

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3
Q

Who was George McGovern?

A

George McGovern was a U.S. Senator who led the Dietary Goals for Americans initiative.

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4
Q

What was the initial focus of McGovern’s committee hearings in 1972?

A

The initial focus was on dietary fat, cholesterol, and heart disease.

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5
Q

What did John Yudkin’s book ‘Sweet and Dangerous’ highlight?

A

It highlighted the urgency of addressing sugar in the diet in relation to diabetes and heart disease.

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6
Q

What was the testimony from Aharon Cohen regarding heart disease?

A

Cohen testified that there was no direct relationship linking heart disease to dietary fats.

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7
Q

What was Peter Cleave’s stance on refined carbohydrates?

A

Cleave believed that the problem extended to all refined carbohydrates and did not support the cholesterol hypothesis.

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8
Q

What did Yudkin blame for heart disease?

A

Yudkin blamed heart disease exclusively on sugar.

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9
Q

What was McGovern’s position on dietary fat and cholesterol?

A

McGovern struggled to reconcile expert testimonies with the belief that dietary fat was the primary cause of heart disease.

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10
Q

What is the fiber hypothesis?

A

The fiber hypothesis posits that the absence of fiber in diets leads to chronic diseases.

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11
Q

Who is Denis Burkitt?

A

Denis Burkitt was a missionary surgeon who proposed the fiber hypothesis after studying disease patterns in Africa.

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12
Q

What did Burkitt conclude about the relationship between fiber and chronic diseases?

A

Burkitt concluded that a lack of fiber leads to conditions such as constipation and related chronic diseases.

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13
Q

How did Burkitt gather evidence for his hypothesis?

A

Burkitt gathered evidence through a network of hospitals reporting on disease cases and dietary habits.

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14
Q

What was the effect of refined carbohydrates according to Burkitt?

A

Refined carbohydrates were linked to constipation and increased risk of diseases like appendicitis and cancer.

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15
Q

What was the dramatic increase in appendicitis cases related to?

A

The increase in appendicitis cases was related to urban populations adopting Western diets.

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16
Q

What did Burkitt’s studies reveal about the health of African populations?

A

African populations maintained low rates of chronic diseases until they adopted Western diets.

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17
Q

What did Burkitt hypothesize about stool transit time?

A

Burkitt hypothesized that reduced fiber slowed stool transit time, increasing the risk of carcinogen damage.

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18
Q

Fill in the blank: Burkitt believed that the absence of _______ in refined carbohydrates leads to chronic diseases.

A

fiber

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19
Q

True or False: Burkitt initially supported the idea that sugar directly caused heart disease.

A

False

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20
Q

What was the general consensus about dietary fat and heart disease by the early 1970s?

A

The consensus was that dietary fat was the primary cause of coronary heart disease.

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21
Q

What did Burkitt’s research in the 1970s conclude about dietary factors?

A

Dietary factors were likely responsible for benign conditions as well as related malignant conditions.

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22
Q

What did Burkitt’s findings suggest about the relationship between Western diets and disease?

A

Western diets were linked to higher incidences of diseases like colorectal cancer, which were rare in traditional diets.

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23
Q

What motivated Burkitt to study stool characteristics and bowel behavior?

A

To associate fiber deficiency, constipation, and chronic diseases.

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24
Q

What was the main finding of Burkitt and Walker’s research published in The Lancet in 1972?

A

Diets with natural fiber resulted in large, soft stools that traverse the intestine rapidly.

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25
What diseases did Burkitt and Walker associate with low-fiber diets?
* Appendicitis * Diverticulitis * Benign tumors of the colon * Malignant tumors of the rectum
26
What was the transformation of Cleave's refined-carbohydrate hypothesis into Burkitt's fiber hypothesis?
The causal agent of disease shifted from the presence of carbohydrates to the absence of fiber.
27
Who was Harold Himsworth and how did he influence Burkitt's work?
A close associate of Burkitt who emphasized the importance of factors absent in disease causation.
28
What was the key message in Burkitt's 1979 diet book?
Don't Forget Fibre in Your Diet.
29
What observations did Hugh Trowell make during his time in East Africa?
The absence of Western diseases among the native population before rapid westernization.
30
What did Trowell conclude about the modern Western diet?
It has a higher ratio of energy to nondigestible fiber, leading to weight gain.
31
What did Burkitt and Trowell identify as a major modification of Cleave's ideas?
The fiber hypothesis.
32
What was the media's reaction to the fiber hypothesis?
It was embraced quickly, with articles promoting fiber as a solution to heart disease and obesity.
33
What was the conclusion of the Dietary Modification Trial of the Women’s Health Initiative published in 2006?
Increasing fiber intake had no beneficial effect on colon cancer, heart disease, or weight loss.
34
True or False: Burkitt's fiber hypothesis has been consistently supported by scientific evidence.
False
35
Fill in the blank: Burkitt and Trowell's hypothesis suggested that a lack of _______ in the diet contributes to chronic diseases.
fiber
36
What did Burkitt's collaborator Alec Walker say about sugar in the diet?
Sugar is an integral part of the daily diet and is here to stay.
37
What did Burkitt argue about the relationship between dietary fat and chronic diseases?
He insisted that the absence of fiber was responsible for chronic diseases, not dietary fat.
38
What was the public health consensus during Burkitt's advocacy for fiber?
Dietary fat and cholesterol were the prime suspects in chronic disease.
39
What did Richard Doll conclude about Burkitt's hypothesis later on?
It has gradually been disproved as a major factor in common diseases of the developed world.
40
What was the primary focus of Burkitt's lectures in the following decade after his initial research?
The dangers of fiber-poor diets and the need to reduce fat intake.
41
What did Trowell's experience in Kenya reveal about the dietary habits of the native population?
They often left food uneaten, indicating that their thinness was not due to food shortages.
42
According to Trowell, what percentage of nutrients in a typical Western diet are available for energy?
93%
43
What did Burkitt and Trowell's 1974 review in The Journal of the American Medical Association discuss?
The causal chain from fiber to constipation and gastrointestinal behavior to Western diseases.
44
What was the initial response to Burkitt's hypothesis from researchers in the United States?
Some blamed colon cancer on dietary fat, while Burkitt insisted it was due to the absence of fiber.
45
What was the initial reception of Burkitt’s hypothesis?
It got accepted pretty well worldwide, quite quickly.
46
What factor does Richard Doll attribute to the gradual disproof of Burkitt’s hypothesis?
Fiber is not a major factor in the common diseases of the developed world.
47
According to Richard Doll, in what context does Burkitt’s hypothesis still hold up?
In relation to constipation.
48
What philosophy influenced the belief in dietary fiber's importance?
Geoffrey Rose’s philosophy of preventive medicine.
49
What did the New England Journal of Medicine editorial conclude about the two major trials on fiber?
Both confirmed that fiber had no effect on colon cancer.
50
Who wrote the editorial accompanying the April 2000 reports on fiber trials?
Tim Byers.
51
What did Tim Byers suggest about the trials on fiber and colon cancer?
They should not be interpreted as evidence against high-fiber diets protecting against later stages of colorectal cancer.
52
True or False: The results of the trials definitively proved that high-fiber diets protect against colorectal cancer.
False.
53
What did the American Cancer Society and the National Cancer Institute continue to suggest?
High-fiber diets might reduce the risk of colon cancer.
54
What role did the media play regarding Burkitt’s hypothesis?
It transformed Burkitt’s hypothesis into dogma without meaningful long-term clinical trials.
55
What did a 1998 Washington Post article claim about diets rich in vegetables and fiber?
They can greatly reduce—or eliminate—the chances of developing colon cancer.
56
Who traditionally wrote about diet and health for the New York Times?
Jane Brody and Marian Burros.
57
What was Jane Brody’s stance on fiber after the negative studies on Burkitt’s hypothesis?
Dietary fiber has myriads of health benefits.
58
What did Kolata suggest misled the public about the benefits of fiber?
The loose use of language in discussing scientific evidence.
59
Fill in the blank: Burkitt’s fiber hypothesis had been based on _______ data.
[hypothesis-generating]
60
What did Burros suggest about fiber in her article following Kolata's discussion?
Fiber significantly lowers the risk of heart attack in women.
61
What conclusion did Brody reach regarding fiber's role in diet by 2004?
Fiber was advocated solely for its alleged ability to induce long-term weight loss.
62
What hypothesis had been forgotten by the time fiber was detached from its original hypothesis?
Cleave’s hypothesis that refined carbohydrates and sugars were the problem.
63
Who described 'Non-infective Diseases in Africa' as a 'brilliant review'?
John Higginson.
64
What was the preferred title over 'diseases of civilization' and why?
'Western diseases' because it was obnoxious to teach that low incidence was due to being uncivilized.