Chapter One Flashcards
Two processes that explain body functions
Teleological (WHY)
Mechanistic (HOW)
Six classifications of physiology
1) Atomic
2)Cellular
3)Tissues
4)organ
5)organ systems
6)organism
Atomic Level
Definition: Formation of molecules (hydrogen and oxygen)
Cellular Level
Definition: Smallest and simplistic
Tissue Level
Definition: collection of similar cells, that are woven together
Sub divisions: Muscle, Nervous, Epithelial, Connective
Muscle Tissue
Skeletal muscle - generates force movement
Smooth muscle - internal
Cardiac muscle - heart, contracts to generate force
Nervous tissue
Central CNS - brain/spinal
Peripheral PNS - nerves/connection
Epithelial tissue
-Found in sheets, covers and lines
-gland formation (endocrine/exocrine)
Cell theory
-cells are smallest structural and functional unit of life
-function of each cell depends on specific structural properties of the cell
-cells are living building blocks of all organisms
Plasma membrane
-Separates ICF and ECF
-controls movement in and out of cell
-transports
-communicates
Nucleus
Contains all DNA of cell
-brain/master molecule
Nuclear envelope
Double layer membrane
Nucleoius
Synthesizes ribosomes
-contains DNA
-transports ribosomes
Chromatin
Spools of DNA, makes up chromosomes
Nuclear ports
Regulates movement of material in and out (Ribosomes)
DNA
Genetic blueprint
-directs protein synthesis
What does cytoplasm break down into (three categories)
-cytosol
-organelles
-inclusions
Cytoplasm
Everything inside cell, excluding the nucleus
Cytosol
Semigelatinous gel like mass
-cytoskeleton is found
-Soluble
ICF
Intercellular fluid, found inside cell
28L
-A part of the cytoplasm
Organelles
Membrane bound, insoluable
“Little organs”
Five organelles
-ER
-golgi complex
-lysosome
-peroxisome
-mitochondria
Endoplasmic reticulum
A network of tubules
-protein and lipid manufactorer
-made up of rough and smooth
Rough ER
Considered rough due to ribosomes layering surface
-site of protein synthesis
Smooth ER
-Transports proteins
-lipid synthesis
-hormone synthesis
-stores calcium in the bones and muscles
Golgi complex
Receives transport vesicles into secretory vesicles
-theorized to be connected to Alzheimer’s
-final destinations
Secretory
Contains all markers for final destinations
-200x larger
Inclusions
Not membrane bound
-insoluable
Inclusions subdivision (three)
-ribosomes
-centrioles
-vault
Lysosome
Used to break down in process of phagocytosis
-full of hydrolytic enzymes
Lysis = degrate
Peroxisome
Produces peroxide
-oxidative reaction enzyme (—> H2O2—>H2O+O2)
Which is larger peroxisome or lysosome
The lysosome is larger
Peroxisome is smaller
Mitochondria
Site of ATP synthesis and storage
-double membrane
-enzyme + citric acid cycle
Ribosome
Site of protein synthesis (mRNA into amino acids)
-from nucleus to cytoplasm
-2 subunits form a complete unit
-80s
-ribosomes can be free floating
-ploy ribosomes exist
Vaults
Used for transportation of ribosomal parts
vaults in cancerous patients THEORY
Vaults store chemotherapy drug, allows resistance to grow against drug
Hydrolytic enzymes
Breakdown
Endocytosis
Process of bringing inside
Phagocytosis
White blood cells consume bad thing, destroys it in a process of the immune system
-lysosomes spray out hydrolytic enzymes to break bad things down
Tay-sachs
No enzyme hexoaminodose (break down glycolipid)
LYSOSOMES
-affects nerve cells
Symptoms include blindness, loss of condition which leads to death
Christaie
Structure in the mitochondria
-energy is created and “jumps” out into the matrix
Matrix
Structure of the mitochondria
-holds energy
McArdle disease
A metabolic deficiency
MITOCHONDRIA
-lacking enzyme to break down glycogen (turns into glucose)
Symptoms include fatigue, pain, cramps
Kearns -Sayre disease
Progressive paralysis due to lack of enzyme in MITOCHONDRIA
-begins with eye muscle—then retinal pigment destroys vision—heart defect into heart blockage (no electrical pulse)
Redox in peroxisome
Breaks down (oxidation reduction)
-H2O2–> H2O + O2
Centrioles
Creates the mitotic spindle, guides DNA movement
-two per cell
-made up by microtubules (9 per centriole)
Centrioles in cancer patient
during cancer treatment centrioles die
-which leads to no cell division
Symptoms include fatigue, diarrhea, hair loss, vomiting