Chap 4 Flashcards
20 days after conception
-neural plate
-neural crest
Neural plate
-contains a lumen
-the CNS
Neural crest
Begins to curl together to form the PNS
-lays on top of the neural plate
28 days after conception
-forebrain
-midbrain
-hindbrain
Hindbrain
The spinal cord
42 days after conception
-cerebrum and diencephalon
-midbrain
-cerebellum, pons and medulla
Central nervous system is made up of
-spinal cord
-brain
spinal cord is made up of
31 pairs
Brain is made up of
-forebrain
-cerebellum
-brain stem
Forebrain is made up of
-cerebrum
-diencephalon
cerebrum is made up of
-Cerebral cortex
-basal nuclei
Diencephalon is made up of
-thalamus
-hypothalamus
Cerebellum made up of three parts
-spinocerebellum
-cerebrocerebellum
-vestibulocerebellum
Brain stem is made up of
-midbrain
-pons
-medulla
Three types of neurons
-afferent
-interneuron
-efferent
What neuron brings information into the CNS
Afferent
what neuron is present completely in the CNS
Interneuron
what neuron takes info from the CNS out
Efferent
Afferent
-advancing to the CNS
-sensory receptor
Anatomy of an afferent neuron
-receptor
-peripheral axon
-central axon (part that enters the CNS)
Interneurons
-very common and complex
-completely in the CNS
-learning and emotions
Efferent
Takes messages from CNS to the target
Neuroglial
The glue that holds neurons together
-support neurons physically and metabolically
Types of neuroglial in the PNS
-satellite cells
-Schwann cells
Satellite cells
Form a shield around cell body, providing health
-part of the PNS
Schwann cells
Form the myelin
-neutrophic growth factors
-found in PNS
Oligiodendrocytes
Insulating myelin sheath in the CNS
-nodes of ranvier
Astrocytes
Paracrine signals to form tight junctions
-blood brain barrier
-enhancing synaptic activities
-physically support
-found in CNS
Microglial
Silent when inactivated
-brain immune cell that scavenges what you don’t need in the brain
Ependymal cells
Secretes the cerebral spinal fluid
-act as stem cells
-found in CNS
Protection of the CNS
-cranium
-3 meningines
-cerebral spinal fluid
Cranium
Hard bony structure, surrounds the brain
The three meningines
-dura mater
-arachnoid mater
-pia mater
Dura mater
Tough outer layer
-venous system, transfers out used blood
Arachnoid mater
Network of projecting
-subarachnoid space
-villi that brings used materials into the venous system
Pia mater
Innermost layer
-attached to brain tissue
-contains arterial system
Meningitis
Infection and inflammation of the three layers
-caused by bacteria
Meningocarpal meningitis
Most fatal of meningitis disease
CSF
Special cushioning fluid
-very salty
-shock absorber
-relives the weight of the brain
-made three times a day only 150mL each time
Why does CSF have high sodium
For quick and efficient communication
Chloroid plexus
Formed by epdymal cells
-produces CSF
-found in 3rd/4th ventricle
Blood brain barrier
Tight junction that is selectively permeable
-produced by astrocytes
What does it mean that the BBB is selectively permeable
-needs carriers for specific communications
Where is the BBB abscent
-brain stem vomiting center
-hypothalamus (ns and endocrine)
Parkinson’s
Deficiency of dopamine production
-movement disorder
Treatment for Parkinson’s
Leva dopa
-crosses BBB then turns into dopamine
Leva dopa
Precursor to dopamine
Cerebrum
Convoluted, highly developed, largest, most distinctive
-contains two cortexes
The cerebrum has __ layers of grey mater
Six
What does grey mater do in the cerebrum
Neuron communication
-found in cerebral cortex
The cerebrum has __ layers of white mater
1
What does white mater do in the cerebrum
Contains all myelinated axons
-found in basal ganglia
Carpus callosum
Neural bridge and communication between both sides
-found in cerebrum
Gyrus and sulcus
Gyrus: peak of swoop
Sulcus: bottom of swoop