Chapter 9 Flashcards
In what ways are ligand-receptor complexes similar to enzyme-substrate complex?
What are the four types of cell signaling?
Define signal transduction pathway
What are the three types of membrane receptors?
What is a G protein?
What is a second messenger?
Why are lipid hormones good for relaying signals across long distances?
Why does estrogen have a different effect in mammary vs uterine cells?
Describe the structure and function of RTKs
Ligand
signaling molecule that binds to a specific receptor protein
Receptor protein
Protein kinase
class of enzyme that adds phosphate groups from ATP to proteins
Phosphate is added to a free —OH on one of the three amino acids:
- Serine
- Threonine
- Tyrosine
Phosphatases
class of enzyme that removes phosphate groups from a protein
Intracellular receptors bind to _______ ligands
hydrophobic
__________ receptors bind to hydrophobic ligands
Intracellular
Cell-surface/membrane receptors bind to ________ ligands
hydrophilic
____________ receptors bind to hydrophilic ligands
Cell-surface/membrane