Chapter 8.1

Question 1

antisedatives

Answer 1

Estazolam, triazolam

Question 2

anti anxiety drugs

Answer 2

diazepam, lorazepam, alprazolam

Question 3

State the mechanism of action of the benzodiazepines for their sedative and antianxiety (anxiolytic) effects.

Answer 3

Increase GABA effects leading to inhibition of CNS

Question 4

zolpidem, zaleplon and eszopiclone mechanism of action

Answer 4

Bind to GABA receptors (alpha receptors)

Question 5

ramelteon mechanism of action

Answer 5

Melatonin recteptor agonist

Question 6

buspirone mechanism of action

Answer 6

stimulate serotonin receptors in CNS

Question 7

State why paroxetine and venlafaxine may be used to treat anxiety and their potential advantages.

Answer 7

Have the ability to influence anxiety with less side effects and less addiction. Can’t influence anxiety attacks

Question 8

Hydroxyzine (Vistaril)

Answer 8

is an antihistamine that treats anxiety

Question 9

Gabapentin (Neurontin) Pregabalin (lyrica) used for

Answer 9

antiseizure and antianxiety`

Question 10

List the major adverse effects of the sedative-hypnotic medications

Answer 10

They are hungover meaning they are confused and have headaches.
Anterograde amnesia: forgot what happened before taking sleeping pill. Your short term memory is affected.

Question 11

List symptoms that may be seen after withdrawal of a benzodiazepine.

Answer 11

BZD’s can cause some sort of neuronal negative effects. Maybe Alzheimers

Question 12

List the non-drug strategies that may be used to manage insomnia.

Answer 12

regular exercise, decreased caffeine, sleeping environment, no TV or phone

Question 13

List the non-drug strategies that may be used to manage anxiety.

Answer 13

Regular exercise, coueceling, relaxation techniques

Question 14

Rebound effect

Answer 14

patient discontinues sleeping pill and gets insomnia again and anxiety can come back when drug is discontinued