Chapter 8: Introduction to Metabolism Flashcards

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1
Q

Cellular Respiration

A

Series of chemical reactions that extracts energy stored in sugars

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2
Q

What is process is cellular respiration needed to perform?

A

WORK

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3
Q

What are three examples of work?

A

1.) Moving solutes against a gradient
2.) Synthesizing macromolecules
3.) Motility

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4
Q

what is metabolism?

A

totality of a cells chemical reactions

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5
Q

metabolism is an….

A

EMERGENT PROPERTY

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6
Q

Explain a metabolic pathway

A

one that begins with a specific molecule and ends with a product

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7
Q

what does each step of a metabolic pathway contain?

A

specific enzymes

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8
Q

What are the two aspects of metabolism?

A

Catabolism & Anabolism

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9
Q

What is catabolism?

A

Process in which cells release energy by breaking down complex molecules into a simpler compound

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10
Q

What is anabolism?

A

process in which cells consume energy to build complex molecules

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11
Q

The study of how energy flows through living organisms

A

Bioenergetics

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12
Q

Are living things open or closed systems?

A

open

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13
Q

What is free energy?

A

portion of a systems energy that can do work when temperature and pressure are uniform in a living cell

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14
Q

When is a reaction sponatenous?

A

when there is a negative delta g, exergonic

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15
Q

What are the 3 main kinds of cellular work?

A

chemical, transport, mechanical

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16
Q

what is the hydrolysis value of ATP?

A

-7.3 kcal/mol

17
Q

How do enzymes speed up processes?

A

by lowering energy barriers

18
Q

What is Ea?

A

activation energy

19
Q

What happens once a substrate binds to an enzymes active site?

A

an induced fit

20
Q

what does the induced fit promote?

A

catalysis

21
Q

what are cofactors?

A

non protein factors needed by some enzymes to assist with catalysis

22
Q

when are enzyme inhibitors irreversible?

A

when they are covalently bonded

23
Q

when are enzyme inhibitors reversible?

A

when they are non covalently bonded

24
Q

what are the two types reversible inhibitors can be?

A

competitive or non-competitive

25
Q

What are competitive inhibitors?

A

they directly bind to the active site, competing with the substrate

26
Q

What are non-competitive inhibitors?

A

they bind to another part of the enzyme, to change the shape of the active site, making it impossible for the substrate to correctly fit into the active site

27
Q

what is allosteric regulation?

A

a regulatory molecule reversibly binds to a protein at one site and affects the proteins function at another

28
Q

What is the one type of inhibition that can be overcome by increasing the substrate concentration?

A

competitive inhibition