chapter 8 Flashcards
activation energy
the initial energy needed to break the bonds of reactants
active site
the region on the enzyme that binds the substrate
allosteric regulation
when a regulatory molecule binds to a protein at one site and affects the proteins function at another site
anabolic pathways
consume energy to build complex molecules from simpler ones
bioenergetics
the study of how energy flows through living organisms
catabolic pathways
release energy by breaking down complex molecules into simpler compunds
catalysis
the process by which a catalyst selectively speeds up a reaction without itself being consumed
catalyst
chemical agent that speeds up a reaction without being consumed
chemical energy
the potential energy available for release in a chemical reaction
coenzymes
organic cofactors
cofactors
nonprotein helpers that bind to the enzyme permanently or reversibly with substrate
competitive inhibitors
closely resemble the substrate and can bind to the enzymes active site
cooperativity
substrate binding to one active site triggering a shape change in the enzyme that stabilizes the active form for all other site
endergonic reaction
absorbs free energy from the surroundings
energy coupling
the use of an exergonic process to drive an endergonic one
entropy
the measure of molecular disorder or randomness
enzyme-substrate complex
when the enzyme and its substrate are bound, before the reaction commences
exergonic reaction
energy outward proceeds with a net release of free energy to the surroundings
feedback inhibition
the end product of a metabolic pathway suts down the pathway
first law of thermodynamics
energy can be transferred and transformed but it cannot be created or destroyed
free energy
the portion of a systems energy that can do work when temperature and pressure are uniform throughout the system (as in a living cell)
induced fit
results from interactions between chemical groups on the substrate and the active site
metabolic pathway
a specific molecule is altered in a series of steps to produce a product. each step is catalyzed by a specific enzyme
metabolism
the totality of an organisms chemical reaction