Chapter 7 Viral Infections Flashcards

1
Q

What is this?

A

pharyngotonsillitis

initial symptoms: fever, sore throat, and headache

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2
Q

Congenital rubella sydnrome triad

A

deafness (80%)

heart disease

cataracts

Virtical transimission during first trimester is 80%

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3
Q

What is this?

A

Herpangina

soft palate and tonsilar pilars

red macules

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4
Q

What is this

A

Rubeola (measles)

Paramyxovirus

resipratory droplets

infectious 2d before symptoms and 4d after rash

Nine day measles: 3 stages with 3 days

First stage: 3 c’s + fever +koplik spots

second stage: rash begins fromt the head down

third stage: rash fades in the same as it presented

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5
Q

What type of virus is the human herpes virus?

A

DNA

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6
Q

What is the histopathology of HSV-1?

A

Multinucleation

Ballooning degeneration: Acanthylosis (separation of cells from each other), Nuclear clearing, and Nuclear enlargement

Tzanck cells (free floating cells)

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7
Q

What is this?

A

VZV

Ramsay Hunt syndrome

Cutaneous lesion of the external auditory canal

Involvement of ipsilateral face and auditory nerves

Facial paralysis

Hearing deficits

Vertigo

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8
Q

What is this?

A

Hand foot and mouth disease

associated with flu-like symptoms

Oral lesions arise first & without prodrome

Resemble those of herpangina, but larger and more numerous
Up to 30 lesions; up to 1 cm in diameter
Affect buccal mucosa, labial mucosa, and tongue most commonly

Cutaneous lesions:

Borders of palms & soles
Ventral surfaces & sides of fingers and toes

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9
Q

CMV

A

Owl eye cells

can reside in salivary gland cells, endothelium, macrophages and lymphocytes

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10
Q

EBV

A

most common presentation is infectious mononucleosis

Other manifestations

Oral hairy leukoplakia

Lymphomas: African’s Burkitt’s lymphoma

Nasopharyngeal carcinoma

Diagnosis is the presence of Paul-Bunnell heterophil antibodies

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11
Q

What is this?

A

Mumps

disease of exocrine glands

25% of post-pubertal males get epididymorchitis

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12
Q

What is this?

A

Primary Herpetic gingivostomatitis

Before age 5

Affects both movable and attached gingiva

Self-inoculation

Leading infectious cause of blindness is HHV

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13
Q

Where do intraoral reccurent HSV-1 infections occur?

A

Always on keratinized bound mucosa

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14
Q

Classification of enteroviruses

A

echoviruses

coxsackievirus

poliovirus

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15
Q

What is this?

A

Oral hairy leukoplakia

EBV (HHV-4)

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16
Q

What is this?

A

Rubella (german measles)

Togavirus

capacity to induce birth defects

3 day measles

Arthritis

17
Q

What is the timetable of an HSV-1 infection?

A

Vesicles rupture in the by day 2

Heals without scaring in 7-10 days

Symptoms are most severe in the first 8h

18
Q

What is this?

A

Koplik spots

Rubeola

paramyxovirus

grains of salt on red background

19
Q

List the types of herpes viruses

A

HSV-1
HSV-2
VZV
EBV
CMV
KSHV

20
Q

What is the tingling sensation you get before a reccurent herpes infection called?

A

Prodrome

21
Q

What is this

A

Forchheimer’s sign

rubella

togavirus

22
Q

Where are HHV-1 and HHV-2 in the latent phase?

A

They are taken up by the sensory nerves and transoported to the associated ganglia

Most common is the trigeminal ganglia

23
Q

What is this?

A

Acute lymphonodular pharyngitis

1-5 yellow to dark-pink nodules on the soft palate and tonsillar pilars

hyperplastic lymphoid aggregates

24
Q

VZV

A

Primary infection is chicken pox

Herpes zoster is recurrence

Latency occurs in dorsal spinal root gangila

If oral lesions occur they are on both attached and unattached gingiva

Terminate at midline because they only affect one side

If tip of the nose in involved it may be a sign that occular involvment can occur and ophthamologist refferal is necessary

25
Q

list other presentations of HSV-1

A

Herpetic whitlow

Herpes gladiatorum or scrumpox

Herpes barbae

26
Q

HIV and AIDS

Oral manifestations

A

CD4+ helper T lymphocytes

Candidiasis (1/3 of HIV and 90% of AIDS)

Hairy leukoplakia

Kaposi’s sarcoma

Non-Hodgkin’s lymphoma

Periodontal disease