chapter 7 Flashcards
the hypothesis, proposed by Beadle and Tatum, that each gene is unique and codes for the synthesis of a single enzyme
one gene- one enzyme hypothesis
the hypothesis that each gene is unique and codes for the synthesis of a single polypeptide; the restated version of the one gene-one enzyme hypothesis
one gene- one polypeptide hypothesis
the fundamental principle of molecular genetics, which states that genetic information flows from DNA to RNA to proteins
central dogma
mechanism by which the information coded in nucleic acids of DNA is copied into the nucleic acids of RNA; something rewritten in the same language
transcription
mechanism by which the information coded in the nucleic acids of RNA is copied into the amino acids of proteins
translation
the end product of the transcription of a gene; is translated by ribosomes into a protein
messenger RNA
a carrier molecule that binds to a specific amino acid and adds the amino acid to the growing polypeptide chain
transfer RNA
an RNA molecule within the ribosome that bonds the correct amino acid to the polypeptide chain
Ribosomal RNA
an enzyme that reads a DNA strand and creates a complementary strand of RNA
RNA polymerase
the DNA strand that is copied into an mRNA molecule during gene transcription
template strand
the initial RNA transcription product
precursor mRNA
the specific coding relationship between bases and the amino acids they specify; the genetic code can be expressed in terms of either DNA or RNA bases
genetic code
a group of three base pairs that code for an individual amino acid
codon
the codon that signals the start of a polypeptide chain and initiates translation
start codon
a codon that signals the end of a polypeptide chain and causes the ribosome to terminate translation
stop codon
a nucleotide sequence that lies just before a gene and allows for the binding of RNA polymerase
promoter
a region of the promoter that enables the binding of RNA polymerase
TATA box
the DNA strand that is not being copied but contains the same sequence as the new RNA molecule
coding strand
a sequence of bases at the end of a gene that signals the RNA polymerase to stop transcribing
termination sequence
a chain of adenine nucleotides that are added to the 3’ end of the pre-mRNA molecule to protect it from enzymes in the cytosol
poly(A) tail