Chapter 6 Flashcards
Blood
Structures of the blood include erythrocytes, leukocytes, thrombocytes, plasma, and other substances. Blood is a connective tissue whose function is to continuously transport those substances throughout the body.
Lymphatic System
Structures of the lymphatic system include lymphatic vessels, lymph fluid, lymph nodes, lymphoid tissues, and lymphoid organs. The function of the lymphatic system is to provide an immune response that defends the body against bacteria, viruses, parasites, foreign cells, and cancer cells.
Agranulocyte
Category of leukocytes with few or no granules in their cytoplasm. It includes lymphocytes and monocytes.
Albumin
Protein molecule that is produced by the liver and carried in the plasma. Albumin exerts osmotic pressure that keeps water from moving out of the blood into the surrounding tissues.
Band
Immature neutrophil in the red bone marrow that has a nucleus shaped like a curved band.
Basophils
Least common type of leukocyte. It is categorized as a granulocyte because it has many large granules in its cytoplasm. These stain dark blue to purple with an alkaline dye.
Bicarbonate
A negatively charged electrolyte in the plasma. Bicarbonate acts as a buffer to maintain the pH of the blood.
Blood type
Genetic material in erythrocytes that determines a person’s blood type. The ABO blood group includes four different blood types: A, B, AB, and O.
Calcium (Ca++)
A positively charged electrolyte in the plasma. Calcium is also factor IV in the process of blood clotting.
Carboxyhemoglobin
Hemoglobin that binds to and carries carbon monoxide in the blood.
Electrolytes
Molecules in the plasma that have a positive or negative electrical charge.
Eosinophil
A type of leukocyte. It is categorized as a granulocyte because it has many large granules in its cytoplasm. These stain bright pink to red with eosin dye.
Erythrocytes
Red blood cell, a round, somewhat flattened disk with no nucleus. An erythroblast is a very immature form that comes from a stem cell.
A reticulocyte is a slightly immature form that is released into the blood.
Erythropoietin
Hormone secreted by the kidneys if the body experiences blood loss. It increases the speed at which erythrocytes are produced and become mature.
Granulocyte
Category of leukocytes with many large granules in their cytoplasm.
Hematopoiesis
Process by which the formed elements of the blood are produced in the red bone marrow, first as very immature cells and then mature cells that are released into the blood.
Hemoglobin
Red, iron-containing molecule in an erythrocyte. Hemoglobin that binds to and carries oxygen from the lungs to the cells is oxyhemoglobin.
Hemoglobin carries carbon dioxide from the cells back to the lungs
Leukocyte
White blood cells. There are five distinct types: neutrophils, eosinophils, basophils, lymphocytes, and monocytes. Each has a specific role in an allergic response or in an immune response.
Lymphocyte
The smallest leukocyte. It is categorized as an agranulocyte as there are few or no granules in its cytoplasm.
A lymphoblastic is an immature form. Lymphoblasts that mature in the re bone marrow become B lymphocytes. Lymphoblasts that migrate to the thymus become t lymphocytes (T cells). Lymphocytes are also known as lymph’s.
Monocyte
The largest leukocyte. It is categorized as an agranulocyte as there are few or no granules in its cytoplasm. It’s nucleus is shaped like a kidney bean. Monocytes are also known as monos.
Neutrophil
Most common type of leukocyte. It is categorized as a granulocyte because it has many large granules in its cytoplasm, but these granules do not stain when there are exposed to laboratory dye, remaining neutral in color.
Oxyhemoglobin
Hemoglobin that is carrying oxygen
Plasma
Clear, straw-colored liquid portion of the blood that transports erythrocytes leukocytes, and thrombocytes, as well as the nutrients of digested foods and the waste products of metabolism
Red bone marrow
Type of connective tissue where all blood cells are produced
Rh blood group
Category of blood type. When the Rh factor is present, the blood is Rh positive. Without the Rh factor, the blood is Rh negative.
Sodium (Na+)
A positively charged electrolyte in the plasma. Sodium exerts osmotic pressure that keeps water from moving out of the blood into the surrounding tissues. This maintains the blood volume and blood pressure.
Stem cell
Original, very immature cell in the red bone marrow that gives rise to all other blood cells, each of which matures in stages to finally become a mature erythrocyte, leukocyte, or thrombocyte that is released into the blood.
Thrombocyte
Cell fragment that is formed form a megakaryocyte, a very large, mature cell with a great deal of cytoplasm. The cytoplasm breaks off into individual thrombocytes. Also known as platelets.
Lymph
Tissue fluid enters a lymphatic capillary and becomes the fluid known as lymph. Lymph flows through the lymphatic system.
Lymph nodes
Small, encapsulated pieces of lymphoid tissue. They are grouped together in chains in areas where there is a high rate of invasion by microorganisms or cancer cells. Special cells in the lymph node destroy any microorganisms or cancer cells in the lymph.
Lymphatic vessels
Structures that begin as capillaries, carry lymph, continue as larger lymphatic vessels, and bring lymph to the lymph nodes.
Lymphoid tissues and organs
Lymphoid tissues include the tonsils and adenoids in the posterior oral cavity, as well as Peter patches and the appendix in the intestines. Lymphoid organs include the thymus and spleen.
Spleen
Lymphoid organ that is posterior to the stomach. The spleen removes old erythrocytes. It is a storage area for whole blood that it releases during times of danger or injury. It contains B cell and T cell lymphocytes.
Thymus
Lymphoid organ in the mediastinum. It receives lymphoblasts that migrate from the red bone marrow, and it helps them mature into several types of T lymphocytes that are part of the immune response.
Aggregation
Process of thrombocytes (platelets) forming clumps to slow down the flow of blood.
Clotting factors
There are 12 clothing factors, numbered I through XIII (there is no factor VI). Platelets release several clotting factors that are activated by the injured blood vessel. Other clotting factors are released from the liver and the injured tissue itself.
Coagulation
Process of the formation of a thrombus (blood clot)
Fibrin
Strands formed by the clotting factors. Fibrin strands trap erythrocytes to form a thrombus (blood clot)
Fibrinogen
Blood clotting factor I that is produced by the liver
Hemostasis
The cessation of bleeding
Prothrombin
Blood clotting factor II that is produce by the liver This clotting factor is activated just before a thrombus is formed.
Serum
Fluid portion of the plasma that remains after the clotting factors are activated to form a blood clot.
Thrombocytes
Thrombocytes (platelets) immediately form clumps to slow down the flow of blood after any injury to a blood vessel.
Thromboplastin
Blood clotting factor III. Also known as tissue factor because it is released from injured tissue.
Thrombus
A blood clot
Allergen
Cells from plants or animals (food,pollen, mold, animal dander), as well as dust, chemicals, and drugs. ANy of these allergens can cause an allergic reaction in a hypersensitive person.
Allergic reaction
An individual’s unique hypersensitivity in response to a certain allergen. Also known as an allergy.
Anaphylaxis
Severe systemic allergic reaction characterized by respiratory distress hypotension and shock.
Basophil
Blood cell that releases histamine during an allergic reaction.
Leukocyte that functions in the immune response by releasing histamine.
Histamine
The basis of the symptoms of an allergic reaction. Histamine is released from basophils in the blood and from mast cells in the connective tissues.
Hypersensitivity
An individuals unique response to an allergen.
Local reaction
An allergic reaction of redness, swelling, and itching in one area.
Example: an allergen contacts the skin or is inhaled into the nose
Systemic Reaction
An allergic reaction throughout the body after an allergen is inhaled, ingested, or injected.
Active immunity
Immune response that is the body’s continuing defense against pathogens it has seen before. It is produced by immunoglobulin G.
Antibody
Antibodies are produced by a B cell when it becomes a plasma cell. Antibodies coat the surface of a bacterium (or virus, or cancer cell, or cell infected with a virus), and this attracts leukocytes to destroy it. Antibodies are also known as immunoglobulins.
B cell
Type of lymphocyte that is inactive until a monocytes presents it with fragments from an eaten pathogen. Then the B cell becomes a plasma cell that produces antibodies.
Complement proteins
Group of proteins in the plasma. When antibodies coat a bacterium (or virus, or cancer cell, or a cell infected with a virus), complement proteins “complement” that effect by drilling holes in them.
Cytotoxic T cell
Type of T cell that kills cells infected with a virus.
Eosinophil
Leukocyte that functions in the immune response by releasing chemicals that destroy foreign cells (pollen, animal dander, dust) and kill parasites.
Helper T cell
Type of T cell that stimulates the production of cytotoxic T cells. When a helper T cell encounters a virus, it produces memory T cells.
Histamine
Released by basophils and mast cells as part of the immune response. It dilates blood vessels and increases blood flow, which brings more leukocytes to the area.
IgA
Immunoglobulin A. Antibody in body secretions (tears, saliva, mucus, and breast milk) and on the skin. It gives passive immunity to a breastfeeding infant.
IgD
Immunoglobulin D. Antibody on the surface of a B cell lymphocyte; it activates the B cell to become a plasma cell.
IgE
Immunoglobulin E. Antibody on the surface of a basophil. It causes the basophil to release histamine.
IgG
Immunoglobulin G. Antibody that provides active immunity. During pregnancy, it crosses the placenta and provides passive immunity to the fetus.
IgM
Immunoglobulin M. Antibody that is produced by plasma cells during the initial exposure to a pathogen. IgM is also produced during a blood transfusion of incompatible blood types.
Immune response
Coordinated effort between leukocytes in the blood and the lymphatic system to identify and destroy invading microorganisms, or foreign cells or cancer cells produced within the body.
Immunoglobulins
Also known as antibodies. There are five classes of immunoglobulins: IgA, IgD, IgE, IgG, IgM
Interferon
Substance produced by a monocytes that has engulfed a virus. Interferon stimulates other cells to produce substances that prevent a virus from entering them to reproduce itself.
Interleukin
Substance produced by a monocyte. It stimulates NK cells to kill cells already infected with a virus. It stimulates B cell and T cell lymphocytes. It also produces the fever that is part of the immune response to inflammation and infection.
Lymphocyte
Leukocyte that function sin the immune response in many different ways.
Memory T cell
Type of T cell that is inactive until a virus enters the body a second time. Then it remembers the virus and becomes a cytotoxic T cell.
Microorganisms
Small living organisms that cause disease. Examples: Bacteria, viruses, Protozoa, fungi, and yeasts.
Monocyte
Leukocyte that engulfs and destroys pathogens that have been coated with antibodies in the process of phagocytosis. It also produces interferon, interleukin, and tumor necrosis factor.
NK (natural killer) cell
Type of lymphocyte that recognizes a cancer cell or a cell infected with a virus and destroys it without the help of an antibody coating.
Neutrophil
Leukocyte that functions in the immune response by engulfing and destroying bacteria in the process of phagocytosis. It also engulfs wastes and foreign substances in the blood.
Passive Immunity
Immune response that occurs when IgG crosses the placenta and fives passive immunity to the fetus. Passive immunity also occur when IgA in the mothers first breast milk (colostrum) is given to the breastfeeding baby. IgG and IgA provide protection from all the diseases the mother has had.
Pathogen
Microorganism that causes disease
Phagocyte
A neutrophil that engulfs and destroys bacteria.
A monocyte that destroys pathogens that have been coated with antibodies. The process of engulfing and destroying is phagocytosis.