Chapter 6 Flashcards
This injectable dissociative anesthetic produces good somatic analgesia by inhibiting the NMDA receptor. It is licensed for use in cats and nonhuman primate
Ketamine
An upgraded version of this drug has the preservative benzyl alcohol which could be toxic to cats especially at high doses
propofol
Although this IV drug does cross the placenta it causes very little neonatal respiratory depression but if given too rapidly to cats can cause red blood cell hemolysis
etomidate
This controlled substance when administered IV should have 1/4 of the calculated dose administered every 15 seconds until the desired effect for ET tube intubation can occur
alfaxalone
This macroemulsion is milky appearing injectable contains egg lecithin glycerin and soybean oil. It is thought to augment the action of GABA. The recommended shelf life once a vial is opened is 6 hours
propofol
This injectable sedative-hypnotic imidazole has minimal cardiovascular and respiratory effects and is thought to augment the action of GABA
etomidate
This injectable dissociative anesthetic is commonly mixed with diazepam and administered IV. When this mixture is administered IV, intubation can occur
ketamine
This injectable dissociative anesthetic agent comes as a combination medication premixed with zolazepam. This combination reduces the risk of seizure and helps promote skeletal muscle relaxation.
tilemine
This IV injectable drug is costly, painful upon injection, and causes nausea and vomiting
etomidate
This injectable dissociative anesthetic is only administered to dogs through an IV route since an IM injection may cause seizure.
ketamine
This injectable dissociative anesthetic agent appears to have less pronounced apneustic breathing than another member of this group
tilemine
This injectable anesthetic agent can be used for sedation, induction and maintenance of anesthesia. It is NOT a DEA controlled substance and does NOT offer analgesia. It is a potent respiratory depressant and rapid injection or high doses can result in life threatening apnea
propofol
This Schedule IV Controlled Substance, is a steroid molecule and is thought to augment the action of GABA
alfaxalone
Constant Rate Infusion (CRI) is not recommended with the use of this IV medication since it depresses adrenal cortical function
etomidate
The dose of this intravenous medication should be administered IV slowly over 1-2 minutes with ¼ the calculated dose administered over 30 seconds
propofol
Propofol enters the brain quickly because
the brain is part of the vessel-rich group of tissues.
propofol is lipid soluble and its entry into the brain is enhanced by the high lipid content of the brain.
What is the term for a breathing pattern in which there is a pause for several seconds at the end of the inspiratory phase, followed by a short, quick expiratory phase
apneustic respiration
The lowest tissue for redistribution/lowest blood flow is
fat
This has the most commonly used inhalant agent in North America
isoflurane
Has the highest percentage of metabolism by the liver
sevoflurane
Highest MAC
nitrous oxide
Can react with exhausted carbon dioxide absorber granules and has the greatest tendency to produce carbon monoxide
desflurane
Has a usual maintenance vaporizer setting between 1.5% and 2.5%
isoflurane
Has the lowest percentage of metabolism by the liver
nitrous oxide
This agent has the highest vaporizer setting and requires an electronic heated vaporizer
desflurane
This halogenated organic compound is best suited to be used for mask or chamber anesthesia induction
sevoflurane
The modern halogenated inhalation agents have a high vapor pressure. This means
they commonly are administered through a precision vaporizer.
if their delivery is not controlled, they could reach a delivery percentage of greater than
30% which could prove fatal to patients.
they easily evaporate from a liquid to a gas
The ability of an inhalation agent to pass through the alveoli of the lung to the blood
stream is related to the…
concentration gradient of the agent in the alveoli
lipid solubility of the agent
The lower the partition coefficient is for an anesthetic means that the agent is better at dissolving in alveolar gas. Therefore, those agents that have lower partition coefficients…
have a faster induction to maintenance anesthesia and a faster recovery
An inhalation anesthetic agent with a higher MAC value will have
a higher precision vaporizer setting for induction and maintenance