Chapter 5 - Ischemia Flashcards

1
Q

Most vulnerable area for ischemia: Brain

A

ACA/MCA/PCA boundary areas (watershed areas)

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2
Q

Neurons most vulnerable to hypoxic-ischemic insults include…

A

Purkinje cells of the cerebellum and pyramidal cells of the hippocampus and neocortex (zones 3, 5, 6)

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3
Q

Most vulnerable area for ischemia: Heart

A

Subendocardium (specially the Left Ventricle)

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4
Q

Most vulnerable area for ischemia: Kidney

A

Straight segment of proximal tubule (medulla)

Thick ascending limb (medulla)

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5
Q

Most vulnerable area for ischemia: Liver

A

Around central vein (zone III)

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6
Q

Most vulnerable area for ischemia: Colon

A

Splenic flexure (Griffith point)

Rectosigmoid junction (Sudeck point)

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7
Q

Definition of a watershed area✅

A

Area with dual blood supply from distal branches of 2 arteries, more susceptible to hypoperfusion

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