Chapter 5 - Ischemia Flashcards
Most vulnerable area for ischemia: Brain
ACA/MCA/PCA boundary areas (watershed areas)
Neurons most vulnerable to hypoxic-ischemic insults include…
Purkinje cells of the cerebellum and pyramidal cells of the hippocampus and neocortex (zones 3, 5, 6)
Most vulnerable area for ischemia: Heart
Subendocardium (specially the Left Ventricle)
Most vulnerable area for ischemia: Kidney
Straight segment of proximal tubule (medulla)
Thick ascending limb (medulla)
Most vulnerable area for ischemia: Liver
Around central vein (zone III)
Most vulnerable area for ischemia: Colon
Splenic flexure (Griffith point)
Rectosigmoid junction (Sudeck point)
Definition of a watershed area✅
Area with dual blood supply from distal branches of 2 arteries, more susceptible to hypoperfusion