Chapter 11 - Inflammation Flashcards by Eduardo Danielli | Brainscape

Q

Mediators of Redness and Warmth

A

Histamine, prostaglandins, bradykinin, NO

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Q

Mediators of Tumor

A

leukotrienes (C4, D4, E4), histamine, serotonin

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Q

Mediators of pain

A

leukotrienes (C4, D4, E4), histamine, serotonin

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Q

Explain Fever

A

Pyrogens (eg, LPS) induce macrophages to release IL-1 and TNF→ ↑ COX activity in perivascular cells of hypothalamus → ↑ PGE2→ ↑ temperature set point

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